Author

P. Sliz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:virus· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Chen· 2 shared H. Peng· 2 shared J. Lu· 2 shared J. Zhang· 2 shared S. Rits-Volloch· 2 shared T. Xiao· 2 shared Y. Cai· 2 shared A. C. Kruse· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

B. Chen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural and functional impact by SARS-CoV-2 Omicron spike mutations

J. Zhang, Y. Cai, C. Lavine, H. Peng, H. Zhu, K. Anand, P. Tong, A. Gautam, M. Mayer, S. Rits-Volloch, S. Wang, P. Sliz, D. Wesemann, W. Yang, M. Seaman, , B. Chen

This study examines the structural, functional, and antigenic properties of the SARS-CoV-2 Omicron spike protein, revealing its enhanced immune evasion and altered fusogenic capability due to mutations.

bioRxiv · Jan 11, 2022Biochemistry

Structural impact on SARS-CoV-2 spike protein by D614G substitution

J. Zhang, Y. Cai, T. Xiao, J. Lu, H. Peng, S. M. Sterling, R. M. Walsh, S. Rits-Volloch, P. Sliz, B. Chen

The paper reports cryo-EM structures of the SARS-CoV-2 spike protein with the D614G substitution, showing how the mutation affects trimer stability and infectivity.

bioRxiv · Oct 13, 2020Biochemistry

Virtual screening identifies novel high-affinity σ1 receptor ligands

H. R. Schmidt, D. A. Greenfield, P. Sliz, A. C. Kruse

The paper uses virtual screening to identify novel high-affinity σ1 receptor ligands, finding 77% of tested compounds bind with high affinity.

bioRxiv · Jul 16, 2019 · PreprintPharmacology & Toxicology