Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
M. G. Kibria, C. L. Lavine, W. Tang, S. Wang, H. Gao, W. Shi, H. Zhu, J. Voyer, S. Rits-Volloch, F. Keerti, C. Bi, H. Peng, D. Wesemann, J. Lu, H. Xie, , B. Chen
This study shows that certain monoclonal antibodies can replace ACE2 to mediate SARS-CoV-2 entry into cells, indicating that ACE2 is not essential for viral infection.
bioRxiv · Feb 20, 2023 · PreprintMicrobiology
W. Shi, Y. Cai, H. Zhu, H. Peng, J. Voyer, S. Rits-Volloch, H. Cao, M. L. Mayer, K. Song, C. Xu, J. Lu, J. Zhang, B. Chen
The paper reports a cryo-EM structure of the SARS-CoV-2 postfusion spike in a membrane, revealing structural details of membrane-interacting segments.
bioRxiv · Dec 5, 2022Biochemistry
J. Zhang, T. Weichun, H. Gao, C. Lavine, W. Shi, H. Peng, H. Zhu, K. Anand, M. Kosikova, H. J. Kwon, P. Tong, A. Gautam, S. Rits-Volloch, S. Wang, M. L. Mayer, , B. Chen
This study characterizes the structural, functional, and antigenic properties of SARS-CoV-2 Omicron BA.2 spike protein and compares its replication efficiency with previous variants.
bioRxiv · Apr 28, 2022 · PreprintMicrobiology
J. Zhang, Y. Cai, C. Lavine, H. Peng, H. Zhu, K. Anand, P. Tong, A. Gautam, M. Mayer, S. Rits-Volloch, S. Wang, P. Sliz, D. Wesemann, W. Yang, M. Seaman, , B. Chen
This study examines the structural, functional, and antigenic properties of the SARS-CoV-2 Omicron spike protein, revealing its enhanced immune evasion and altered fusogenic capability due to mutations.
bioRxiv · Jan 11, 2022Biochemistry
J. Zhang, T. Xiao, Y. Cai, C. L. Lavine, H. Peng, H. Zhu, K. Anand, P. Tong, A. Gautam, M. L. Mayer, R. M. Walsh, S. Rits-Volloch, D. R. Wesemann, W. Yang, M. S. Seaman, , B. Chen
This study compares the structure, function, and antigenicity of the SARS-CoV-2 Delta variant's spike protein with other variants, showing its enhanced membrane fusion and transmissibility.
bioRxiv · Aug 17, 2021Biochemistry
Y. Cai, J. Zhang, T. Xiao, C. L. Lavine, S. Rawson, H. Peng, H. Zhu, K. Anand, P. Tong, A. Gautam, S. Lu, S. Sterling, R. M. Walsh, S. Rits-Volloch, J. Lu, , B. Chen
This study reports cryo-EM structures of SARS-CoV-2 variants B.1.1.7 and B.1.351, revealing mutations that enhance infectivity and immune evasion.
bioRxiv · Apr 13, 2021Biochemistry
T. Xiao, J. Lu, J. Zhang, R. I. Johnson, L. G. A. McKay, N. Storm, C. L. Lavine, H. Peng, Y. Cai, S. Rits-Volloch, S. Lu, B. D. Quinlan, M. Farzan, M. S. Seaman, A. Griffiths, B. Chen
This study creates a trimeric ACE2 variant with high affinity for SARS-CoV-2 spike protein and shows it inhibits viral infection in cell culture.
Nature Structural & Molecular Biology · Feb 1, 2021Peer-reviewedMicrobiology
J. Zhang, Y. Cai, T. Xiao, J. Lu, H. Peng, S. M. Sterling, R. M. Walsh, S. Rits-Volloch, P. Sliz, B. Chen
The paper reports cryo-EM structures of the SARS-CoV-2 spike protein with the D614G substitution, showing how the mutation affects trimer stability and infectivity.
bioRxiv · Oct 13, 2020Biochemistry
Y. Cai, J. Zhang, T. Xiao, H. Peng, S. M. Sterling, R. M. Walsh, S. Rawson, S. Rits-Volloch, B. Chen
The paper reports two cryo-EM structures of the SARS-CoV-2 spike protein, showing prefusion and postfusion conformations, and discusses their implications for viral entry and immune evasion.
bioRxiv · May 16, 2020Biochemistry