Author

P. Zimmermann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

J.-P. Borg· 4 shared G. David· 3 shared L. Camoin· 3 shared A. Goubard· 2 shared C. Fauriat· 2 shared J. Fares· 2 shared M. Aurrand-Lions· 2 shared M. Balzano· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCancer Biology

J.-P. Borg

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Downregulation of stromal syntenin sustains AML development

R. Leblanc, R. Ghossoub, A. Goubard, R. Castellano, J. Fares, L. Camoin, S. Audebert, M. Balzano, B. Boutayeh, C. Fauriat, N. Vey, J.-P. Borg, Y. Collette, M. Aurrand-Lions, G. David, P. Zimmermann

This study shows that reduced stromal syntenin in bone marrow stromal cells promotes AML aggressiveness by enhancing AML cell survival and protein synthesis through endoglin upregulation.

bioRxiv · Feb 15, 2023Cancer Biology

Structural basis for targeting the human T-cell leukemia virus Tax oncoprotein and syntenin-1 interaction using a small molecule

S. Maseko, I. Van Molle, K. Blibek, C. Gorgulla, J. Olivet, J. Blavier, C. Vandermeulen, S. Skupiewski, D. Saha, T. Ntombela, J. Lim, F. Lembo, A. Beauvois, M. Hamaidia, J.-P. Borg, , J.-C. Twizere

This study identifies the structural basis of Tax-1 interaction with syntenin-1 and demonstrates small-molecule inhibition of this interaction to target HTLV-1.

bioRxiv · Aug 25, 2021 · PreprintBiochemistry

A syntenin-deficient microenvironment educates AML for aggressiveness

R. Leblanc, J. Fares, A. Goubard, R. Castellano, L. Camoin, M. Balzano, R. Ghossoub, B. Bou-Tayet, C. Fauriat, N. Vey, J.-P. Borg, Y. Collette, M. Aurrand-Lions, G. David, P. Zimmermann

This study shows that syntenin-deficiency in the bone marrow microenvironment promotes AML aggressiveness by enhancing cell survival through autophagy and protein synthesis.

bioRxiv · Jan 6, 2021 · PreprintCancer Biology

PLD2-phosphatidic acid recruit ESCRT-I to late endosomes for exosome biogenesis.

A. L. Egea-Jimenez, S. Audebert, M. Castro-Cruz, J.-P. Borg, G. David, L. Camoin, P. Zimmermann

The paper shows PLD2 and phosphatidic acid recruit ESCRT-I to late endosomes, facilitating exosome biogenesis through MVB12B interactions.

bioRxiv · Nov 25, 2020 · PreprintCell Biology

The Flemmingsome reveals an ESCRT-to-membrane coupling required for completion of cytokinesis

C. Addi, A. Presle, S. Fremont, F. Cuvelier, M. Rocancourt, F. Milin, S. Schmutz, J. Chamot-Rooke, T. Douche, M. Duchateau, Q. Giai Gianetto, H. Menager, M. Matondo, P. Zimmermann, N. Gupta-Rossi, A. Echard

The paper identifies a plasma membrane-to-ESCRT module essential for abscission, showing its role in cytokinesis, exosome formation, and HIV budding.

bioRxiv · Jan 15, 2020Cell Biology