RELB Reprograms Exhausted Tumor-Infiltrating Lymphocytes for Improved Adoptive Cell Therapy
Christian D. McRoberts Amador, Rachel E. Conover, Michael C. Brown, Liliana Lyniv, Pamela Noldner, Ying Zhou, Aretha R. Gao, Sean R. McCutcheon, Scott Joseph Antonia, Charles A. Gersbach
This study identifies RELB as a key regulator that enhances TIL expansion and function, improving adoptive cell therapy for solid tumors.
bioRxiv · Oct 11, 2025 · PreprintBioengineering