Author

Kirit Singh

Duke Medical CenterORCID 0000-0002-0419-5381Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Beth H. ShaziD· 2 shared Katayoun AyasoufiiD· 2 shared Kelly M. HotchkissiD· 2 shared Mustafa KhasrawiD· 2 shared Anna M. CorcoraniD· 1 shared Bhairavy J. PuviindraniD· 1 shared Chelsea O. Railton· 1 shared Eliese MoelkeriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Beth H. ShazORCID

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2 papers

Recent·Most cited

Cancer BiologyJournal of Clinical InvestigationPeer-reviewedApr 17, 2025

IL-7-mediated expansion of autologous lymphocytes increases CD8+ VLA-4 expression and accumulation in glioblastoma models

Kirit Singh, Kelly M. Hotchkiss, Sarah L. Cook…·Peter Edward Fecci

This study shows that IL-7-expanded autologous lymphocytes increase VLA-4 expression and accumulate in glioblastoma tumors, enhancing the effectiveness of T cell-based therapies.

9 citations

mousehuman

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Cancer BiologybioRxivPreprintMar 26, 2025

Spatial and Cellular Architecture of the Glioblastoma Microenvironment Associated with Tumor-Infiltrating Lymphocyte Expansion

Kelly M. Hotchkiss, Kenan Zhang, Anna M. Corcoran…·Mustafa Khasraw

The paper examines TIL expansion in glioblastoma by analyzing spatial organization and myeloid context, finding that TIL+ tumors have distinct immune interactions and vascular niches.

2 citations

humanbulk RNA-seq

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