Author
IRBM
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Antonino Missineo, Licia Tomei, Nadine Alaimo…·Elizabeth M. Doherty
This paper develops and validates recombinant monoclonal antibodies that selectively detect specific huntingtin neoepitopes, addressing variability in existing antibodies and enabling new research into huntingtin fragment cleavage mechanisms.
Margherita Verani, Paola Martufi, Lara Petricca…·Cristina Cariulo
The paper develops an ultrasensitive immunoassay to detect S421 phosphorylation of huntingtin in HD models and nonhuman primate CSF, linking it to disease progression and identifying PRKACA as a kinase involved.
Cristina Cariulo, Paola Martufi, Margherita Verani…·Andrea Caricasole
The paper shows IKBKB reduces mutant huntingtin aggregation by phosphorylating S13 via a non-canonical IKK pathway.
Ramanath Narayana Hegde, Anass Chiki, Lara Petricca…·Hilal Ahmed Lashuel
This study identifies TBK1 as a kinase that phosphorylates mutant huntingtin, reduces its aggregation and toxicity in multiple HD models.