MKK4 and MKK7 control degeneration of retinal ganglion cell somas and axons after glaucoma-relevant injury.
Olivia J. Marola, Stephanie B. Syc‐Mazurek, Sarah E. R. Yablonski, Peter G. Shrager, Simon W. M. John, Richard T. Libby
This study shows MKK4 and MKK7 drive RGC soma and axon degeneration after glaucoma injury, while DDIT3/JUN only prevent soma loss but not axon degeneration.
Cell Death Discovery · Dec 15, 2025Peer-reviewedPathology