Brian E. Wadzinski

Development and application of nbLIBRA-seq for high-throughput discovery of antigen-specific nanobodies

This paper develops and validates nbLIBRA-seq, a method for high-throughput antigen-specific nanobody discovery in immunized alpacas, demonstrating its effectiveness in identifying nanobodies against CD71 and viral antigens.

Novel COX-2 Targeted Nanobodies for Molecular Endoscopic Imaging of Colorectal Adenomas

This paper develops COX-2-targeted nanobodies for enhanced endoscopic imaging of colorectal adenomas, showing tumor-specific accumulation in vivo.

The role of liprin-α1 phosphorylation in its liquid-liquid phase separation: regulation by PPP2R5D/PP2A holoenzyme

This study identifies PPP2R5D/PP2A holoenzyme as an inhibitor of liprin-1 liquid-liquid phase separation through regulation of phosphorylation sites.

Neuronal protein phosphatase 1β regulates glutamate release, cortical myelination, node of Ranvier formation, and action potential propagation in the optic nerve

This study investigates the role of PP1β in neuronal function by deleting it in mice, revealing its impact on myelination, glutamate release, and action potential propagation.