Sandra Clauder‐Münster

Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy

This study uses base editors and AAVMYO to correct Rbm20 mutations in cardiomyocytes, improving splicing and cardiac function in mouse models of dilated cardiomyopathy.

Patient-derived gene and protein expression signatures of NGLY1 deficiency

The paper characterizes gene and protein expression changes in NGLY1 deficiency using patient-derived cells and provides a web resource for the data.

Condensin controls cellular RNA levels through the accurate segregation of chromosomes instead of directly regulating transcription

This study shows condensin affects RNA levels by causing chromosome missegregation, not by directly regulating transcription.