Author

Pu-Yao Zhang

Peking University Third Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Mo LiiD· 2 shared Yang YuiD· 2 shared Yong FaniD· 2 shared Baolei YuaniD· 1 shared Chenrui AniD· 1 shared Chongwei BiiD· 1 shared Enbo ZhangiD· 1 shared Gerardo Ramos‐MandujanoiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersDevelopmental Biology

Mo LiORCID

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2 papers

Recent·Most cited

Generation of human blastocyst-like structures from pluripotent stem cells

Yong Fan, Zheying Min, Samhan M. Alsolami, Zhenglai Ma, Enbo Zhang, Wei Chen, Ke Zhong, Wendi Pei, Xiangjin Kang, Pu-Yao Zhang, Yongliang Wang, Yingying Zhang, Linfeng Zhan, Haiying Zhu, Chenrui An, , Yang Yu

This paper describes a method to generate blastocyst-like structures from human pluripotent stem cells and shows they resemble blastocysts in morphology and transcriptome.

Cell Discovery · Sep 7, 2021Peer-reviewedDevelopmental Biology

Single-cell Individual Complete mtDNA Sequencing Uncovers Hidden Mitochondrial Heterogeneity in Human and Mouse Oocytes

Chongwei Bi, Lin Wang, Yong Fan, Gerardo Ramos‐Mandujano, Baolei Yuan, Xuan Zhou, Jincheng Wang, Yanjiao Shao, Pu-Yao Zhang, Yanyi Huang, Yang Yu, Juan Carlos Izpisúa Belmonte, Mo Li

This paper introduces iMiGseq, a method for ultra-sensitive mtDNA sequencing in oocytes, revealing hidden heterogeneity and deleterious variants in human and mouse samples.

bioRxiv · Dec 28, 2020 · PreprintGenomics