Author

R. A. Kittles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. R. Murphy· 1 shared A. Woloszynska· 1 shared B. Karanam· 1 shared C. Hughes Halbert· 1 shared C. Yates· 1 shared D. J. Smiraglia· 1 shared E. C. Gomez· 1 shared G. Azabdaftari· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. R. Murphy

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Author profile →

3 papers

Recent·Most cited

Vitamin D receptor cistrome-transcriptome analyses establishes quantitatively distinct receptor genomic interactions in African American prostate cancer regulated by BAZ1A

M. Siddappa, S. Hussain, S. A. Wani, H. Tang, H. Jafari, J. S. Gray, M. D. Long, I. Elhussin, B. Karanam, H. Wang, R. Morgan, G. Hardiman, I. B. Adelani, S. Rotimi, A. R. Murphy, , M. J. Campbell

The paper analyzes VDR genomic interactions in African American prostate cancer cells and identifies BAZ1A as a regulator of VDR-dependent transcriptional responses.

bioRxiv · Jan 31, 2022 · PreprintCancer Biology

Racial differences in androgen metabolism and receptor signaling in prostate cancer

S. Ramakrishnan, E. C. Gomez, K. Attwood, R. A. Kittles, J. Wang, S. R. Rosario, D. J. Smiraglia, G. Azabdaftari, J. L. Mohler, W. J. Huss, A. Woloszynska

This study identifies racial differences in androgen metabolism and receptor signaling in prostate cancer, showing African American men use an alternative pathway for DHT biosynthesis associated with disease progression.

bioRxiv · Mar 31, 2021 · PreprintCancer Biology

Role of CYP3A5 in modulating androgen receptor signaling and its relevance to African American men with prostate cancer

P. Gorjala, O. B. Goodman, R. A. Kittles, R. Mitra

This study shows that CYP3A5 modulates androgen receptor signaling in prostate cancer cells from African American men, with inducers enhancing and inhibitors reducing AR activity and cell growth.

bioRxiv · Jan 24, 2020Cancer Biology