Author
R. A. Neher
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2016-2023 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 13 mutual co-author links10 papers
Recent·Most cited
Evolution of the SARS-CoV-2 mutational spectrum
J. D. Bloom, A. C. Beichman, R. A. Neher, K. Harris
This study analyzes changes in the mutation spectrum of SARS-CoV-2 across millions of sequences, finding shifts in mutation rates, particularly a decrease in G[->]T mutations in Omicron compared to early clades.
bioRxiv · Nov 19, 2022Evolutionary Biology
A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike
B. Dadonaite, K. H. Crawford, C. E. Radford, A. G. Farrell, T. C. Yu, W. W. Hannon, P. Zhou, R. Andrabi, D. R. Burton, L. Liu, D. D. Ho, R. A. Neher, J. D. Bloom
This paper introduces a pseudovirus system for deep mutational scanning of SARS-CoV-2 spike protein mutations, showing how they affect antibody neutralization and infection.
bioRxiv · Oct 13, 2022Microbiology
Characterising the epidemic spread of Influenza A/H3N2 within a city through phylogenetics
N. F. Müller, D. Wüthrich, N. Goldman, N. Sailer, C. Saalfrank, M. Brunner, N. Augustin, H. M. Seth-Smith, Y. Hollenstein, M. Syedbasha, D. Lang, R. A. Neher, O. Dubuis, M. Naegele, A. Buser, , T. Stadler
The paper uses genetic sequence data and patient metadata to analyze local influenza transmission dynamics in Basel, Switzerland, finding that temperature trends correlate with transmission and that elderly and school children drive different transmission networks.
bioRxiv · Apr 27, 2020Evolutionary Biology
Evolution, geographic spreading, and demographic distribution of Enterovirus D68
E. B. Hodcroft, R. Dyrdak, C. Andres, A. Egli, J. Reist, D. G. Martinez de Artola, J. Alcoba Florez, H. G. M. Niesters, A. Anton, R. Poelman, M. Reynders, E. Wollants, R. A. Neher, J. Albert
This study analyzes the evolution and geographic spread of EV-D68 using genomic data from 2018, revealing distinct subclades and age-related patterns in infection.
bioRxiv · Jan 10, 2020Microbiology
Stability of association between Arabidopsis thaliana and Pseudomonas pathogens over evolutionary time scales
T. L. Karasov, J. Almario, C. Friedemann, W. Ding, M. Giolai, D. Heavens, S. Kersten, D. S. Lundberg, M. Neumann, J. Regalado, R. A. Neher, E. Kemen, D. Weigel
The paper surveys Pseudomonas in Arabidopsis thaliana over multiple years and sites, finding that pathogenic sublineages coexist without a single dominant strain overtaking populations.
bioRxiv · Jan 30, 2018Microbiology
Nextstrain: real-time tracking of pathogen evolution
J. Hadfield, C. Megill, S. M. Bell, J. Huddleston, B. Potter, C. Callender, P. Sagulenko, T. Bedford, R. A. Neher
Nextstrain provides real-time tracking of pathogen evolution by integrating viral genome data with other public health data through a database, bioinformatics pipeline, and visualization platform.
bioRxiv · Nov 22, 2017Evolutionary Biology
Rapid and consistent evolution of colistin resistance in Pseudomonas aeruginosa during morbidostat culture
B. Regenbogen, M. Willmann, M. Steglich, B. Bunk, U. Nubel, S. Peter, R. A. Neher
This study shows that colistin resistance in Pseudomonas aeruginosa evolves rapidly and consistently in morbidostat cultures, with mutations targeting specific genes involved in lipopolysaccharide synthesis and signaling.
bioRxiv · Oct 14, 2016Microbiology