Author

R. B. Russell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Organism:Drosophila· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

G. D. Diwan· 3 shared e. lorentzen· 2 shared K. Boldt· 2 shared K. Junger· 2 shared A. Banito· 1 shared A. Carazzato· 1 shared A. M. Dobberkau· 1 shared A. Mourao· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

G. D. Diwan

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

DLG1 functions upstream of SDCCAG3 and IFT20 to control ciliary targeting of polycystin-2

C. K. Rezi, M. Aslanyan, G. D. Diwan, T. Cheng, M. Chamlali, K. Junger, Z. Anvarian, e. lorentzen, K. B. Pauly, Y. Bahadori, E. F. Fernandes, F. Qian, S. Tosi, S. T. Christensen, S. F. Pedersen, , L. B. Pedersen

This study shows DLG1 regulates ciliary protein trafficking in kidney cells, with loss of DLG1 causing ciliary elongation and cysts, and a specific DLG1 variant linked to kidney disease.

bioRxiv · Nov 10, 2023Cell Biology

Multidimensional Characterization of Soft-Tissue Sarcomas with FUS-TFCP2 or EWSR1-TFCP2 Fusions

J. Schopf, S. Uhrig, C. E. Heilig, K.-S. Lee, T. Walther, A. Carazzato, A. M. Dobberkau, D. Weichenhan, C. Plass, M. Hartmann, G. D. Diwan, Z. Carrero, C. R. Ball, T. Hohl, T. Kindler, , C. Scholl

This study characterizes soft-tissue sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions through multi-omics analyses and functional studies, identifying therapeutic targets and mechanisms of disease.

bioRxiv · Feb 19, 2023Cancer Biology

Ciliopathy-associated missense mutations in IFT140 are hypomorphic and have edgetic effects on protein interaction networks

T. Leonhard, G. D. Diwan, F. Klose, I. F. Stehle, K. Junger, M. Seda, S. Bolz, F. Woerz, R. B. Russell, K. Boldt, D. Jenkins, M. Ueffing, T. Beyer

This study investigates how missense mutations in IFT140 affect protein interactions and complex stability, revealing hypomorphic and edgetic effects in ciliopathy-related diseases.

bioRxiv · Jan 18, 2023Cell Biology

Biochemically validated structural model of the 15-subunit IFT-B complex

N. A. Petriman, M. Loureiro-Lopez, M. Taschner, N. K. Zacharia, M. M. Georgieva, N. Boegholm, A. Mourao, R. B. Russell, J. S. Andersen, E. Lorentzen

The paper presents a biochemically validated structural model of the 15-subunit IFT-B complex using AlphaFold and experimental validation techniques.

bioRxiv · Aug 20, 2022 · PreprintBiochemistry

The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+ cells indicate a high degree of conservation to mammalian palmitoylomes

E. Porcellato, J. C. Gonzalez, C. Ahlmann-Eltze, M. A. Elsakka, I. Shapira, J. Fritsch, J. A. Navarro, S. Anders, R. B. Russell, F. T. Wielnad, C. Metzendorf

The paper presents the first systematic analysis of the Drosophila S2R+ cell palmitoylome and demonstrates the utility of DHHC-BioID for identifying DHHC-PAT client proteins.

bioRxiv · Dec 6, 2021Biochemistry

RhoGAP19D inhibits Cdc42 laterally to control epithelial cell shape and prevent invasion

W. Fic, R. Bastock, F. Raimondi, E. Los, Y. Inoue, J. Gallop, R. B. Russell, D. St Johnston

The paper identifies RhoGAP19D as a Cdc42 GTPase Activating Protein that restricts Cdc42 activity to the apical domain, preventing epithelial invasion.

bioRxiv · Sep 17, 2020Cell Biology