Author

M. Taschner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:biophysical modeling· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

S. Gruber· 4 shared E. Lorentzen· 2 shared A. Mourao· 1 shared B. Steigenberger· 1 shared C. Basquin· 1 shared C. Dekker· 1 shared D. Soulard· 1 shared F. P. Bock· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersBiochemistry

S. Gruber

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

All eukaryotic SMC proteins induce a twist of -0.6 at each DNA-loop-extrusion step

R. Janissen, R. Barth, I. F. Davidson, M. Taschner, S. Gruber, J.-M. Peters, C. Dekker

The paper measures the twist induced by eukaryotic SMC proteins during DNA loop extrusion and finds all three SMC complexes induce a consistent -0.6 twist per step.

bioRxiv · Mar 22, 2024 · PreprintBiophysics

A conserved antigen induces respiratory Th17-mediated serotype-independent protection against pneumococcal superinfection

X. Liu, L. Van Maele, L. Matarazzo, D. Soulard, V. Alves Duarte da Silva, V. de Bakker, J. Denereaz, F. P. Bock, M. Taschner, S. Gruber, V. Nizet, J.-C. Sirard, J.-W. Veening

The paper identifies a conserved antigen, LafB, that provides serotype-independent protection against pneumococcal superinfection via Th17 cells, independent of antibodies.

bioRxiv · Jul 7, 2023 · PreprintMicrobiology

DNA segment capture by Smc5/6 holo-complexes

M. Taschner, S. Gruber

The paper describes how Smc5/6 complexes load and capture DNA segments through a mechanism involving the Nse5/6 loader and kleisin neck gate.

bioRxiv · Oct 9, 2022Biochemistry

Biochemically validated structural model of the 15-subunit IFT-B complex

N. A. Petriman, M. Loureiro-Lopez, M. Taschner, N. K. Zacharia, M. M. Georgieva, N. Boegholm, A. Mourao, R. B. Russell, J. S. Andersen, E. Lorentzen

The paper presents a biochemically validated structural model of the 15-subunit IFT-B complex using AlphaFold and experimental validation techniques.

bioRxiv · Aug 20, 2022 · PreprintBiochemistry

Nse5/6 inhibits the Smc5/6 ATPase to facilitate DNA substrate selection.

M. Taschner, J. Basquin, B. Steigenberger, I. Schaefer, Y.-M. Soh, C. Basquin, E. Lorentzen, M. Raeschle, R. A. Scheltema, S. Gruber

The paper shows Nse5/6 inhibits Smc5/6 ATPase activity, modulating DNA substrate selection in yeast.

bioRxiv · Feb 9, 2021Biochemistry