Author

J. Im

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. A. Saleh· 1 shared A. Futreal· 1 shared A. Lim· 1 shared A. Sivan· 1 shared B. Fleming· 1 shared B. Smiley· 1 shared C. Coker· 1 shared C. Liams· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBioengineering

A. A. Saleh

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Author profile →

6 papers

Recent·Most cited

Forage conservation is a neglected nitrous oxide source

S. Yang, M. Mahmood, R. Baral, H. Wu, M. Almloff, L. Stanton, D. Min, B. Smiley, C. Liams, J. Yu, J. Im

This study investigates N2O emissions from forage conservation and finds it could be a significant source, with chlorate reducing emissions but other factors having no effect.

bioRxiv · Mar 19, 2024Bioengineering

Colorectal cancer detection and treatment with engineered probiotics

C. R. Gurbatri, G. Radford, L. Vrbanac, C. Coker, J. Im, S. R. Taylor, Y. Jang, A. Sivan, K. Rhee, A. A. Saleh, T. Chien, F. Zandkarimi, I. Lia, T. R. Lannagan, T. Wang, , T. Danino

This paper demonstrates the use of engineered probiotics to detect and treat colorectal cancer by monitoring their colonization and delivering therapeutic molecules.

bioRxiv · Apr 3, 2023 · PreprintBioengineering

ABC-transporter CFTR folds with high fidelity through a modular, stepwise pathway

J. Im, T. Hillenaar, H. Y. Yeoh, P. Sahasrabudhe, M. Mijnders, M. van Willigen, P. van der Sluijs, I. Braakman

This study reveals the stepwise folding pathway of CFTR, showing two distinct stages of domain folding and assembly, with implications for understanding protein misfolding diseases.

bioRxiv · Jul 20, 2022Biochemistry

A Cytosolic Reductase Pathway is Required for Complete N-Glycosylation of an STT3B-Dependent Acceptor Site.

M. van Lith, M. A. Pringle, B. Fleming, G. Gaeta, J. Im, J. R. Gilmore, N. J. Bulleid

The paper shows that a cytosolic reductive pathway is needed for complete N-glycosylation at an STT3B-dependent site, linking cytosolic redox conditions to glycosylation efficiency.

bioRxiv · Aug 31, 2021Cell Biology

Single-cell Characterization of Acute Myeloid Leukemia and its Microenvironment Following PD-1 Blockade Based Therapy

H. A. Abbas, D. Hao, K. Tomczak, P. Baroodia, J. Im, P. K. Reville, Z. Alaniz, W. Wang, R. Wang, F. Wang, G. Al-Atrash, K. Takahashi, J. Ning, M. Ding, J. Matthews, , A. Futreal

This study analyzes single-cell RNA and TCR profiles from AML patients before and after PD-1 blockade therapy to identify factors influencing response and resistance.

bioRxiv · Sep 3, 2020Cancer Biology

Sapphire-Supported Nanopores for Low-Noise DNA Sensing

P. Xia, J. Zuo, P. Paudel, S. Choi, X. Chen, W. Song, J. Im, C. Wang

This paper introduces sapphire-supported nanopore membranes with reduced capacitance and noise, improving DNA sensing accuracy and speed compared to silicon-supported nanopores.

bioRxiv · Mar 2, 2020Bioengineering