Author

R. Boutry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

P. Froguel· 3 shared A. Bonnefond· 2 shared A. Abderrahmani· 1 shared A. Khamis· 1 shared A. Tomas· 1 shared B. Jones· 1 shared C. Bourouh· 1 shared C. Carney· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCell Biology

P. Froguel

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Author profile →

3 papers

Recent·Most cited

Control of human pancreatic beta cell kinome by GLP-1R biased agonism

J. Xiao, L. Eleid, T. Buenaventura, R. Boutry, A. Bonnefond, B. Jones, G. A. Rutter, P. Froguel, A. Tomas

This study compares kinase activity profiles in human pancreatic beta cells stimulated by GLP-1R agonists with different bias, revealing distinct kinomic responses and potential therapeutic targets.

bioRxiv · Feb 25, 2023Cell Biology

A crosstalk between E2F1 and GLP-1 signaling pathways modulates insulin secretion

C. Bourouh, E. Courty, G. Pasquetti, X. Gromada, N. Rabhi, C. Carney, M. Moreno, R. Boutry, L. Rolland, E. Caron, Z. Benfodda, P. Meffre, J. Kerr-Conte, F. Pattou, P. Froguel, , J.-S. Annicotte

This study shows that E2F1 and GLP-1 signaling pathways interact to regulate insulin secretion and glucose homeostasis in beta cells.

bioRxiv · Apr 16, 2021Physiology

Histone deacetylase 9 promoter hypomethylation associated with adipocyte dysfunction is a statin-related metabolic effect

A. Khamis, R. Boutry, M. Canouil, S. Mathew, S. Lobbens, H. Crouch, T. Andrew, A. Abderrahmani, F. Tamanini, P. Froguel

This study identifies statin-induced hypomethylation of the HDAC9 promoter and its link to adipocyte dysfunction and insulin resistance in T2D risk.

bioRxiv · Nov 23, 2019Cell Biology