Author

L. ElEid

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Tomas· 3 shared B. Jones· 3 shared G. A. Rutter· 2 shared Y. Manchanda· 2 shared A. Bonnefond· 1 shared A. I. Oqua· 1 shared A. Montoya· 1 shared A. Muller· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

A. Tomas

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GLP-1R associates with VAPB and SPHKAP at ERMCSs to regulate β-cell mitochondrial remodelling and function

G. Austin, A. I. Oqua, L. ElEid, M. Zhu, Y. Manchanda, P. Peres, H. Coyle, Y. Poliakova, K. Bouzakri, A. Montoya, D. J. Withers, M. Solimena, B. Jones, S. J. Millership, S. Burgold, , A. Tomas

This study shows GLP-1R agonists improve mitochondrial health in beta-cells by forming a complex with VAPB and SPHKAP at ER-mitochondria MCSs, leading to mitochondrial remodelling and improved function.

bioRxiv · Apr 28, 2024Cell Biology

Control of human pancreatic beta cell kinome by GLP-1R biased agonism

J. Xiao, L. Eleid, T. Buenaventura, R. Boutry, A. Bonnefond, B. Jones, G. A. Rutter, P. Froguel, A. Tomas

This study compares kinase activity profiles in human pancreatic beta cells stimulated by GLP-1R agonists with different bias, revealing distinct kinomic responses and potential therapeutic targets.

bioRxiv · Feb 25, 2023Cell Biology

Divergent acute versus prolonged pharmacological GLP-1R responses in adult beta cell-selective β-arrestin 2 knockout mice

S. Bitsi, Y. Manchanda, L. ElEid, N. Mohamed, B. Hansen, K. Suba, G. A. Rutter, V. Salem, B. Jones, A. Tomas

This study examines GLP-1R responses in beta cell-specific β-arrestin 2 knockout mice, finding acute deficits and prolonged effects with certain agonists.

bioRxiv · Apr 21, 2022 · PreprintCell Biology