Author

R. Briggs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:multiple species· 1

Frequent Co-Authors

A. Bardelli· 1 shared A. Ceci· 1 shared A. K. Sharp· 1 shared A. M. Brown· 1 shared A. R. Goldberg· 1 shared A. U. Lindner· 1 shared C. D. Kailing· 1 shared C. J. Scott· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Bardelli

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Widespread exposure to SARS-CoV-2 in wildlife communities

A. R. Goldberg, K. E. Langwig, K. L. Brown, J. M. Marano, P. Rai, K. M. King, A. K. Sharp, A. Ceci, C. D. Kailing, M. J. Kailing, R. Briggs, M. G. Urbano, C. Roby, A. M. Brown, J. Weger-Lucarelli, , J. R. Hoyt

The paper documents SARS-CoV-2 exposure in six wildlife species and finds higher seroprevalence in areas with high human activity, suggesting human-to-animal transmission events.

bioRxiv · Nov 4, 2022Ecology

Bcl-xL is a key mediator of apoptosis following KRASG12C inhibition in KRASG12C mutant colorectal cancer.

H. Khawaja, R. Briggs, C. Latimer, M. Rassel, D. Griffin, L. Hanson, A. Bardelli, F. Di Nicolantonio, S. S. McDade, C. J. Scott, S. Lambe, M. Maurya, A. U. Lindner, J. H. M. Prehn, J. Sousa, , S. Van Schaeybroeck

This study identifies Bcl-xL as a mediator of resistance to KRASG12C inhibitors in colorectal cancer and shows that combining Bcl-xL inhibition with KRASG12C inhibition enhances apoptosis and reduces tumor growth.

bioRxiv · May 10, 2022Cancer Biology