Author

R. Ferris

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Angione· 1 shared A. C. Tarbay· 1 shared A. Cillo· 1 shared A. Duensing· 1 shared A. Hefner· 1 shared A. Kulkarni· 1 shared A. Li· 1 shared A. N. Mallela· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

A. Angione

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Author profile →

3 papers

Recent·Most cited

All-trans retinoic acid induces durable tumor immunity in IDH-mutant gliomas by rescuing transcriptional repression of the CRBP1-retinoic acid axis

A. Rao, X. Zhang, A. Cillo, J. H. Sussman, P. Sandlesh, A. C. Tarbay, A. N. Mallela, C. Cardello, K. Krueger, J. Xu, A. Li, J. Xu, J. Patterson, E. Akca, A. Angione, , N. M. Amankulor

This study shows that all-trans retinoic acid (ATRA) improves immune response in IDH-mutant gliomas by restoring the RA pathway, leading to tumor regression in mouse models and a clinical trial for human patients.

bioRxiv · Apr 9, 2024 · PreprintCancer Biology

An individualized causal framework for learning intercellular communicationnetworks that define microenvironments of individual tumors

X. Chen, L. Chen, C. H. L. Kurten, F. Jabbari, L. Vujanovic, Y. Ding, B. Lu, K. Lu, A. Kulkarni, T. Tabib, R. Lafyatis, G. F. Cooper, R. Ferris, X. Lu

The paper develops a causal framework to identify tumor-specific intercellular communication networks in head and neck squamous cell carcinoma, revealing subtype-specific patterns linked to clinical outcomes.

bioRxiv · Nov 11, 2021Cancer Biology

Inhibition of histone acetyltranserase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a novel gain of function.

M. Kumar, D. Molkentine, J. Molkentine, K. Bridges, T. Xie, L. Yang, A. Hefner, M. Gao, M. J. Frederick, S. Seth, M. Abdelhakiem, B. Beadle, F. M. Johnson, J. Wang, L. Shen, , H. D. Skinner

The paper identifies CREBBP/EP300 as radiosensitization targets in mutant tumors by inhibiting histone acetyltransferase, which represses homologous recombination and increases radiation sensitivity.

bioRxiv · Apr 10, 2020 · PreprintCancer Biology