Author

R. Geha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

A. R. Leferts· 1 shared C. E. Wobus· 1 shared C. Kharas· 1 shared C. M. Bassis· 1 shared D. Huynh· 1 shared D. Irvine· 1 shared E. Janssen· 1 shared G. Nunez· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. R. Leferts

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Natural IgA and TNFRSF13B polymorphism: a double edged sword fueling balancing selection

J. L. Platt, M. G. de Mattos Barbosa, D. Huynh, A. R. Leferts, J. Katta, C. Kharas, P. Freddolino, C. M. Bassis, C. E. Wobus, R. Geha, R. J. Bram, G. Nunez, N. Kamada, M. Cascalho

The paper investigates how a dominant-negative variant of TNFRSF13B confers resistance to enteric pathogens by reducing natural IgA, suggesting balancing selection due to its dual role in immunity and pathogenesis.

bioRxiv · Jan 29, 2021 · PreprintImmunology

Cytoskeletal tension actively sustains the migratory T cell synaptic contact

S. Kumari, M. Mak, Y. Poh, M. Tohme, N. Watson, M. Melo, E. Janssen, M. Dustin, R. Geha, D. Irvine

This study identifies a mechanical mechanism involving cytoskeletal tension that sustains T cell-APC synaptic contact symmetry and stability.

bioRxiv · May 4, 2019Cell Biology