Author

R. Gruber

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 1 Biochemistry· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:non-human primate· 2 Assay:behavioral assay· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Organism:human· 1 Organism:multiple species· 1

Frequent Co-Authors

A. Alekseeva· 1 shared A. B. Krug· 1 shared A. Bisio· 1 shared A. Frohnwieser· 1 shared A. H. Taylor· 1 shared A. Naggi· 1 shared C. Mandel· 1 shared C. Reiter· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

A. Alekseeva

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Author profile →

4 papers

Recent·Most cited

Comparative CNS Pharmacology of the Brutons Tyrosine Kinase (BTK) Inhibitor Tolebrutinib Versus Other BTK Inhibitor Candidates for Treating Multiple Sclerosis.

T. J. TURNER, P. Brun, R. Gruber, D. Ofengeim

This paper compares the CNS pharmacology of three BTK inhibitors in non-human primates, finding that tolebrutinib achieves higher CSF exposure than the others.

bioRxiv · Mar 25, 2024Pharmacology & Toxicology

Pentosan polysulfate inhibits attachment and infection by SARS-CoV-2 in vitro: insights into structural requirements for binding.

S. Bertini, A. Alekseeva, S. Elli, I. Pagani, S. Zanzoni, G. Eisele, R. Krishnan, K. P. Maag, C. Reiter, D. Lenhart, R. Gruber, E. A. Yates, E. Vicenzi, A. Naggi, A. Bisio, M. Guerrini

This study shows that pentosan polysulfate inhibits SARS-CoV-2 attachment and infection in vitro, with effectiveness comparable to heparin and better than low molecular weight heparin.

bioRxiv · Dec 19, 2021 · PreprintBiochemistry

Binding of phosphatidylserine-positive microparticles by PBMCs classifies disease severity in COVID-19 patients

L. Rausch, K. Lutz, M. Schifferer, E. Winheim, R. Gruber, L. Rinke, J. Hellmuth, C. Scheerer, M. Muenchhoff, C. Mandel, M. Bergwelt-Baildon, M. Simons, T. Straub, A. B. Krug, J. Kranich, T. Brocker

The paper identifies PS+ PMPs as a marker for disease severity in COVID-19 by showing their correlation with immune dysfunction and clinical outcomes.

Journal of Extracellular Vesicles · Dec 1, 2021Peer-reviewedImmunology

Decision-making flexibility in New Caledonian crows, young children and adult humans in a multi-dimensional tool-use task

R. Miller, R. Gruber, A. Frohnwieser, M. Schiestl, S. A. Jelbert, R. D. Gray, M. Boeckle, A. H. Taylor, N. S. Clayton

This study compares decision-making flexibility in New Caledonian crows, children, and humans during a tool-use task, finding differences in tool selection and adaptability to complexity.

bioRxiv · Jul 4, 2019Animal Behavior & Cognition