Author

R. Hasan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Evolutionary Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Kelley· 1 shared A. Patnaik· 1 shared A. Solanki· 1 shared A. Swarbrick· 1 shared B. Ahmed· 1 shared B. Labadie· 1 shared C. C. Macip· 1 shared C. Drovetsky· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. Kelley

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Gene Therapy Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice

C. C. Macip, R. Hasan, V. Hoznek, J. Kim, L. E. Metzger, S. Sethna, N. Davidsohn

This study shows that partial reprogramming using OSK factors in aged mice extends lifespan and improves healthspan, with potential implications for reversing age-related diseases.

bioRxiv · Jan 4, 2023Bioengineering

Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer

K. Chaudagar, H. M. Hieromnimon, R. Khurana, B. Labadie, T. Heirz, S. Mei, R. Hasan, J. Shafran, A. Kelley, E. Apostolov, G. Al-Eryani, K. Harvey, S. Rameshbabu, M. Loyd, K. Bynoe, , A. Patnaik

The paper shows that inhibiting lactate production in tumor cells suppresses PTEN/p53-deficient prostate cancer growth by activating macrophage phagocytosis.

bioRxiv · May 12, 2022Cancer Biology

A plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation

C. E. Mackay, M. Floen, M. D. Leo, R. Hasan, C. Fernandez-Pena, P. Singh, K. U. Malik, J. H. Jaggar

This study shows that PC-1 and PC-2 form a complex in endothelial cells that mediates flow-induced vasodilation through Ca2+ influx and NOS activation.

bioRxiv · Oct 16, 2021Physiology

Molecular evolution and genetic analysis of Mesta yellow vein mosaic virus and associated betasatellites

R. Ahmed, R. Hasan, M. W. Ullah, B. Ahmed

This study analyzes the molecular evolution and genetic diversity of Mesta yellow vein mosaic virus and its associated betasatellites in the Indian subcontinent, identifying recombination, selection pressures, and geographic influences on their evolution.

bioRxiv · Sep 5, 2021 · PreprintEvolutionary Biology