Author

R. J. Tower

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

A. W. James· 2 shared E. F. McCarthy· 2 shared Q. Qin· 2 shared A. Lu· 1 shared C. A. Meyers· 1 shared C. Chen· 1 shared C. D. Morris· 1 shared F. Long· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

A. W. James

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NELL-1 regulates the matrisome to alter osteosarcoma disease progression

Q. Qin, M. Gomez-Salazar, R. J. Tower, L. Chang, C. D. Morris, E. F. McCarthy, K. Ting, X. Zhang, A. W. James

This study shows NELL-1 promotes osteosarcoma progression by altering the matrisome, with loss of NELL-1 reducing invasion and improving survival in both human and mouse models.

bioRxiv · Jan 21, 2022 · PreprintCancer Biology

NGF-p75 signaling coordinates skeletal cell migration during bone repair

J. Xu, Z. Li, R. J. Tower, S. Negri, Y. Wang, C. A. Meyers, T. Sono, Q. Qin, A. Lu, X. Xing, E. F. McCarthy, T. L. Clemens, A. W. James

This study identifies NGF-p75 signaling as critical for coordinating skeletal cell migration during bone repair by affecting osteogenic precursor migration and bone healing.

bioRxiv · Jul 7, 2021Cell Biology

Single cell transcriptomics identifies a unique adipocyte population that regulates bone marrow environment

L. Zhong, L. Yao, R. J. Tower, Y. Wei, Z. Miao, J. Park, R. Shrestha, L. Wang, W. Yu, N. Holdreith, Y. Zhang, W. Tong, Y. Gong, F. Long, J. Ahn, , L. Qin

The paper identifies a unique adipocyte population in bone marrow, MERAs, that regulate bone and vessel homeostasis through single-cell transcriptomics in mice.

bioRxiv · Sep 11, 2019 · PreprintCell Biology