Author

H. L. Dugan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. T. Stamper· 3 shared J. J. Guthmiller· 3 shared L. Li· 3 shared M. Huang· 3 shared N.-Y. Zheng· 3 shared O. Stovicek· 3 shared P. C. Wilson· 3 shared S. Changrob· 3 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

C. T. Stamper

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Evolution of antibody immunity following Omicron BA.1 breakthrough infection

C. I. Kaku, T. N. Starr, P. Zhou, H. L. Dugan, P. Khalife, G. Song, E. R. Champney, D. W. Mielcarz, J. C. Geoghegan, D. R. Burton, R. Andrabi, J. D. Bloom, L. M. Walker

This study tracks antibody responses six months after Omicron BA.1 breakthrough infection and finds reduced neutralizing antibodies and memory B cells, with public clones dominating and predicting new sublineages.

bioRxiv · Sep 21, 2022 · PreprintImmunology

Librator, a platform for optimized sequence editing, design, and expression of influenza virus proteins

L. Li, O. Stovicek, J. J. Guthmiller, S. Changrob, Y. Fu, H. L. Dugan, C. T. Stamper, N.-Y. Zheng, M. Huang, P. C. Wilson

Librator is a platform for sequence editing and design of influenza virus proteins, enabling efficient mutation and chimeric protein creation for vaccine development.

bioRxiv · Apr 29, 2021 · PreprintMicrobiology

A public broadly neutralizing antibody class targets a membrane-proximal anchor epitope of influenza virus hemagglutinin

J. J. Guthmiller, J. Han, H. A. Utset, L. Li, L. Y.-L. Lan, C. Henry, C. T. Stamper, O. Stovicek, L. Gentles, H. L. Dugan, N.-Y. Zheng, S. T. Richey, M. E. Tepora, D. J. Bitar, S. Changrob, , P. C. Wilson

This study identifies a class of broadly neutralizing antibodies targeting a conserved membrane-proximal epitope on influenza HA, showing their induction by a chimeric HA vaccine.

bioRxiv · Feb 25, 2021 · PreprintImmunology

Human antigen-specific memory natural killer cell responses develop against HIV-1 and influenza virus and are dependent on MHC-E restriction

S. Jost, O. Lucar, T. Yoder, K. Kroll, S. Sugawara, S. Smith, R. Jones, G. Tweet, A. Werner, P. J. Tomezsko, H. L. Dugan, J. Ghofrani, M. Altfeld, A. Grundhoff, M. Muller-Trutwin, , R. K. Reeves

This study shows human NK cells develop antigen-specific memory against HIV-1 and influenza via MHC-E restriction, validated through single-cell cloning and biomarker analysis.

bioRxiv · Nov 9, 2020 · PreprintImmunology

SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike

J. J. Guthmiller, O. Stovicek, J. Wang, S. Changrob, L. Li, P. Halfmann, N.-Y. Zheng, H. Utset, C. T. Stamper, H. L. Dugan, W. D. Miller, M. Huang, Y.-N. Dai, C. A. Nelson, P. D. Hall, , P. C. Wilson

This study finds that severe SARS-CoV-2 infection is associated with stronger antibody and memory B cell responses against the spike protein and nucleocapsid protein.

bioRxiv · Sep 12, 2020Immunology