Author

R. Khattri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Parker· 1 shared A. Wong· 1 shared B. D. Horning· 1 shared B. F. Cravatt· 1 shared B. N. Newby· 1 shared C. E. Mathews· 1 shared C. L. Eissler· 1 shared D. V. Serreze· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Parker

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Author profile →

2 papers

Recent·Most cited

Selective inhibitors of JAK1 targeting a subtype-restricted allosteric cysteine

M. E. Kavanagh, B. D. Horning, R. Khattri, N. Roy, J. P. Lu, L. R. Whitby, J. C. Brannon, A. Parker, J. M. Chick, C. L. Eissler, A. Wong, J. L. Rodriguez, S. Rodiles, K. Masuda, J. R. Teijaro, , B. F. Cravatt

This study identifies an allosteric cysteine in JAK1 and TYK2, develops inhibitors targeting it, and shows high subtype selectivity with minimal off-target effects.

bioRxiv · Jan 31, 2022 · PreprintPharmacology & Toxicology

Human CD8+ T-cells Require Glycolysis to Elicit Effector Function

S. E. Stimpson, J. Chen, B. N. Newby, R. Khattri, H. D. Chapman, T. E. Angelini, M. E. Merritt, D. V. Serreze, C. E. Mathews

This study shows glycolysis is essential for CD8+ T-cell effector function, while mitochondrial respiration is not, and inhibiting glycolysis reduces autoimmunity in a diabetes model.

bioRxiv · Feb 5, 2020 · PreprintImmunology