Author

M. E. Kavanagh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

B. F. Cravatt· 2 shared A. F. Hazel· 1 shared A. Parker· 1 shared A. R. Huber· 1 shared A. Ruffini· 1 shared A. Wong· 1 shared B. D. Horning· 1 shared C. L. Cole· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

B. F. Cravatt

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Author profile →

2 papers

Recent·Most cited

Glutathione supports lipid abundance in vivo

G. Asantewaa, E. T. Tuttle, N. P. Ward, Y. P. Kang, Y. Kim, M. E. Kavanagh, N. Girnius, Y. Chen, R. Duncan, K. Rodriguez, F. Hecht, M. Zocchi, L. Smorodintsev-Schiller, T. Q. Scales, K. Taylor, , I. S. Harris

This study shows that glutathione (GSH) is essential for lipid abundance in adult tissues, particularly in the liver, by repressing NRF2.

bioRxiv · Feb 10, 2023 · PreprintBiochemistry

Selective inhibitors of JAK1 targeting a subtype-restricted allosteric cysteine

M. E. Kavanagh, B. D. Horning, R. Khattri, N. Roy, J. P. Lu, L. R. Whitby, J. C. Brannon, A. Parker, J. M. Chick, C. L. Eissler, A. Wong, J. L. Rodriguez, S. Rodiles, K. Masuda, J. R. Teijaro, , B. F. Cravatt

This study identifies an allosteric cysteine in JAK1 and TYK2, develops inhibitors targeting it, and shows high subtype selectivity with minimal off-target effects.

bioRxiv · Jan 31, 2022 · PreprintPharmacology & Toxicology