Author

R. Khoriaty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3 Evolutionary Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

D. Ginsburg· 3 shared B. McGee· 2 shared B. T. Emmer· 2 shared B. Zhang· 2 shared D. Siemieniak· 2 shared T. Saunders· 2 shared A. B. Ozel· 1 shared A. Bernard· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPhysiology

D. Ginsburg

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Hepatic inactivation of murine Surf4 results in marked reduction in plasma cholesterol

V. T. Tang, J. McCormick, B. Xu, Y. Wang, H. Fang, X. Wang, D. Siemieniak, R. Khoriaty, B. T. Emmer, X.-W. Chen, D. Ginsburg

This study shows that reducing SURF4 in the liver decreases PCSK9 and increases LDLR, leading to lower plasma cholesterol despite reduced lipoprotein secretion.

bioRxiv · Aug 1, 2022Physiology

A common SEC23B missense mutation in congenital dyserythropoietic anemia type II leads to growth restriction and chronic pancreatitis in mice

W. Wei, Z. Liu, C. Zhang, R. Khoriaty, M. Zhu, B. Zhang

This study shows that a common SEC23B mutation in mice causes chronic pancreatitis and growth restriction, highlighting SEC23B's role in pancreatic function and growth hormone sensitivity.

bioRxiv · May 10, 2021Cell Biology

The ER cargo receptor SURF4 facilitates efficient erythropoietin secretion

Z. Lin, R. King, V. Tang, G. Myers, G. Balbin-Cuesta, A. Friedman, B. McGee, K. Desch, A. B. Ozel, D. Siemieniak, P. Reddy, B. Emmer, R. Khoriaty

This study identifies SURF4 as an ER cargo receptor that facilitates EPO secretion and suggests its modulation could treat erythropoiesis disorders.

bioRxiv · Dec 6, 2019Cell Biology

Murine Surf4 is essential for early embryonic development

B. T. Emmer, P. J. Lascuna, E. Kotnik, T. Saunders, R. Khoriaty, D. Ginsburg

This study shows that Surf4 is essential for early embryonic development in mice, as Surf4-/- embryos die between E3.5 and E9.5, while Surf4+/- mice are normal.

bioRxiv · Feb 7, 2019Cell Biology

The Function of the COPII Gene Paralogs SEC23A and SEC23B Are Interchangeable In Vivo

R. Khoriaty, G. Hesketh, A. Bernard, A. C. Weyand, D. Mellacheruvu, G. Zhu, M. J. Hoenerhoff, B. McGee, L. Everett, E. J. Adams, B. Zhang, T. Saunders, A. Nesvizhskii, D. J. Klionsky, J. A. Shavit, , D. Ginsburg

This study shows SEC23A and SEC23B are functionally interchangeable in vivo, suggesting phenotypic differences arise from gene expression rather than protein function.

bioRxiv · Nov 7, 2017Evolutionary Biology