Author

R. M. Wasnick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 4

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Assay:bulk RNA-seq· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

S. Bellusci· 4 shared A. Guenther· 3 shared J. Wilhelm· 3 shared A. I. Vazquez-Armendariz· 2 shared C. Chen· 2 shared C. Ruppert· 2 shared E. El Agha· 2 shared I. Shalashova· 2 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersCell Biology

S. Bellusci

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Author profile →

4 papers

Recent·Most cited

Cell-surface PD-L1 expression identifies a sub-population of distal epithelial cells enriched in idiopathic pulmonary fibrosis

N. Ahmadvand, G. Carraro, M. Jones, I. Shalashova, J. Wihelm, N. Baal, F. Kosravi, C. Chen, J. Zhang, A. Guenther, R. M. Wasnick, S. Bellusci, C. Ruppert

The paper identifies CD274-expressing cells in human lungs that are expanded in IPF and show progenitor-like behavior in ex vivo assays.

bioRxiv · Mar 9, 2022 · PreprintCell Biology

Identification a novel subset of alveolar type 2 cells expanding following pneumonectomy and enriched in PD-L1

N. Ahmadvand, F. Khosravi, A. Lingampally, R. M. Wasnick, A. I. Vazquez-Armendariz, M. Heiner, S. Rivetti, Y. Lv, J. Wilhelm, A. Gunther, S. Herold, D. M. Al Alam, C. Chen, P. Minoo, J. Zhang, S. Bellusci

The paper identifies a novel subset of quiescent alveolar type 2 cells in mice that expand after pneumonectomy and are enriched in PD-L1, with similar findings observed in human lungs.

bioRxiv · May 20, 2020Cell Biology

Restored alveolar epithelial differentiation and reversed human lung fibrosis upon Notch inhibition

R. M. Wasnick, M. Korfei, K. Piskulak, I. Henneke, J. Wilhelm, P. Mahavadi, D. von der Beck, M. Koch, I. Shalashova, O. Klymenko, L. Fink, H. Witt, H. Hackstein, E. El Agha, S. Bellusci, , A. Guenther

Notch1 inhibition restores alveolar epithelial differentiation, reduces surface tension, and reverses matrix deposition in lung fibrosis.

bioRxiv · Mar 23, 2019 · PreprintCell Biology

Metformin induces lipogenic differentiation in myofibroblasts to reverse mouse and human lung fibrosis

V. Kheirollahi, R. M. Wasnick, V. Biasin, A. I. Vazquez-Armendariz, X. Chu, A. Moiseenko, A. Weiss, J. Wilhelm, J.-S. Zhang, G. Kwapiszewska, S. Herold, R. T. Schermuly, W. Seeger, A. Guenther, S. Bellusci, E. El Agha

This study shows metformin reduces lung fibrosis by inducing lipogenic differentiation in myofibroblasts through BMP2-PPARγ signaling and AMPK-dependent collagen reduction.

bioRxiv · Sep 26, 2018Cell Biology