Author

E. El Agha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

S. Bellusci· 3 shared A. Guenther· 2 shared J. Wilhelm· 2 shared R. M. Wasnick· 2 shared S. Herold· 2 shared W. Seeger· 2 shared A. I. Vazquez-Armendariz· 1 shared A. Lingampally· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCell Biology

S. Bellusci

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Author profile →

3 papers

Recent·Most cited

Lineage-tracing of Acta2+ cells in aged mice during lung fibrosis formation and resolution supports the lipofibroblasts to myofibroblast reversible switch

A. Lingampally, M. Truchi, O. Mauduit, V. Delcroix, S. Hadzic, J. Koepke, A.-I. Vazquez-Armendariz, S. Herold, C. Samakovlis, H. Makarenkova, E. El Agha, C. Chen, B. Mari, S. Bellusci

This study traces Acta2+ cells in aged mice during lung fibrosis to show lipofibroblasts can reversibly switch to myofibroblasts, with similar patterns observed in humans.

bioRxiv · Feb 19, 2024 · PreprintPathology

Restored alveolar epithelial differentiation and reversed human lung fibrosis upon Notch inhibition

R. M. Wasnick, M. Korfei, K. Piskulak, I. Henneke, J. Wilhelm, P. Mahavadi, D. von der Beck, M. Koch, I. Shalashova, O. Klymenko, L. Fink, H. Witt, H. Hackstein, E. El Agha, S. Bellusci, , A. Guenther

Notch1 inhibition restores alveolar epithelial differentiation, reduces surface tension, and reverses matrix deposition in lung fibrosis.

bioRxiv · Mar 23, 2019 · PreprintCell Biology

Metformin induces lipogenic differentiation in myofibroblasts to reverse mouse and human lung fibrosis

V. Kheirollahi, R. M. Wasnick, V. Biasin, A. I. Vazquez-Armendariz, X. Chu, A. Moiseenko, A. Weiss, J. Wilhelm, J.-S. Zhang, G. Kwapiszewska, S. Herold, R. T. Schermuly, W. Seeger, A. Guenther, S. Bellusci, E. El Agha

This study shows metformin reduces lung fibrosis by inducing lipogenic differentiation in myofibroblasts through BMP2-PPARγ signaling and AMPK-dependent collagen reduction.

bioRxiv · Sep 26, 2018Cell Biology