Author

R. Marches

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

D. Nehar-Belaid· 2 shared J. Banchereau· 2 shared A. P. Lakshmanan· 1 shared A. Terranegra· 1 shared B. A. Kabeer· 1 shared C. Smitherman· 1 shared C.-h. Chung· 1 shared D. Bedognetti· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

D. Nehar-Belaid

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3 papers

Recent·Most cited

An unconventional mechanism of IL-1β secretion that requires Type I IFN in lupus monocytes

S. Caielli, P. Balasubramanian, J. Rodriguez-Alcazar, U. Balaji, Z. Wan, J. Baisch, C. Smitherman, L. Walters, P. Sparagana, D. Nehar-Belaid, R. Marches, L. Nassi, K. Stewart, J. Fuller, J. F. Banchereau, , V. Pascual

The paper identifies an unconventional IL-1β secretion mechanism in lupus monocytes requiring Type I IFN, involving mitochondrial RNA and the NLRP3 inflammasome.

bioRxiv · Aug 3, 2023 · PreprintImmunology

Sexual-dimorphism in human immune system aging

E. J. Marquez, C.-h. Chung, R. Marches, R. J. Rossi, D. Nehar-Belaid, D. J. Mellert, G. A. Kuchel, J. Banchereau, D. Ucar

The paper examines sex differences in immune system aging using ATAC-seq, RNA-seq, and flow-cytometry on peripheral blood mononuclear cells from 172 adults, revealing sex-specific epigenomic and functional changes with aging.

bioRxiv · Feb 7, 2020Immunology

Elevation of FAM129A in neutrophils exposed to serum of patients with severe sepsis: in silico investigations during a hands on training workshop and follow on validation of protein expression in neutrophils

J. Roelands, L. Chiche, R. Marches, M. Toufiq, B. A. Kabeer, M. A. I. Alfaki, M. Saadaoui, A. P. Lakshmanan, D. K. Bangarusamy, S. Murugesan, D. Bedognetti, W. Hendrickx, S. A. Khodor, A. Terranegra, J. Banchereau, , D. Rinchai

The paper investigates FAM129A expression in neutrophils exposed to sepsis serum using transcriptome data and confirms surface expression through bench validation.

bioRxiv · Jan 25, 2019 · PreprintImmunology