Author

R. Prins

Primary ORCID profile (0000-0001-9775-6709 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

R. PrinsiD2 papers · CenGen (Pty) Ltd

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Hara· 1 shared A. Hari· 1 shared A. Kaminitz· 1 shared A. Lee· 1 shared A. Madi· 1 shared A. von Deimling· 1 shared B. Ruf· 1 shared C. Kraemer· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Hara

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors

M. Kilian, R. Sheinin, C. L. Tan, C. Kraemer, M. Friedrich, A. Kaminitz, K. Sanghvi, K. Lindner, F. Cichon, S. Jung, K. Jaehne, M. Ratliff, R. Prins, A. von Deimling, W. Wick, , M. Platten

This study shows that MHC class II antigen presentation on blood-borne myeloids is essential to maintain functional CD8+ T cells in brain tumors by preventing Tox-driven dysfunction.

Cancer Cell · Feb 1, 2023Peer-reviewedCancer Biology

MAIT cells have a negative impact on glioblastoma

S. keretsu, T. Hana, A. Lee, N. Kedei, N. Malik, H. Kim, J. Spurgeon, G. Khayrullina, B. Ruf, A. Hara, M. Coombs, M. Watowich, M. Watanabe, A. Hari, M. K. B. Ford, , M. Terabe

The paper identifies MAIT cells as immunosuppressive in glioblastoma, correlating their presence with poor patient survival and immune suppressive gene upregulation.

bioRxiv · Jul 17, 2022 · PreprintImmunology