Author

R. R. Goel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 6

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Organism:human· 6 Research Focus:cell type annotation· 4 Assay:flow cytometry· 4 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Assay:CITE-seq· 1

Frequent Co-Authors

A. E. Baxter· 5 shared A. Pattekar· 5 shared D. Mathew· 5 shared E. J. Wherry· 5 shared J. Dougherty· 5 shared J. R. Giles· 5 shared M. M. Painter· 5 shared O. Kuthuru· 5 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersImmunology

A. E. Baxter

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies

M. M. Painter, T. S. Johnston, K. A. Lundgreen, J. J. S. Santos, J. S. Qin, R. R. Goel, S. A. Apostolidis, D. Mathew, B. Fulmer, J. C. Williams, M. L. McKeague, A. Pattekar, A. Goode, S. Nasta, A. E. Baxter, , E. J. Wherry

The paper examines immune responses in vaccinated individuals during SARS-CoV-2 breakthrough infection, showing early activation of memory T cells and subsequent neutralizing antibody production.

bioRxiv · Feb 5, 2023 · PreprintImmunology

A long interval between priming and boosting SARS-CoV-2 mRNA vaccine doses enhances B cell responses with limited impact on T cell immunity

A. Nicolas, G. Sannier, M. Dube, M. Nayrac, M. M. Painter, R. R. Goel, M. Laporte, H. R. Medjahed, J. Williams, N. Brassard, J. Niessl, L. Gokool, C. Morrisseau, P. Arlotto, C. Tremblay, , D. E. Kaufmann

This study shows that a longer interval between SARS-CoV-2 mRNA vaccine doses enhances B cell responses but has minimal impact on T cell immunity.

bioRxiv · Aug 3, 2022 · PreprintImmunology

Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19

S. A. Apostolidis, A. Sarkar, H. M. Giannini, R. R. Goel, D. Mathew, A. Suzuki, A. E. Baxter, A. R. Greenplate, C. Alanio, M. Abdel-Hakeem, D. A. Oldridge, J. R. Giles, J. E. Wu, Z. Chen, Y. J. Huang, , E. J. Wherry

This study identifies FcγRIIA and C5a-C5aR pathways as mediators of platelet hyperactivation in COVID-19 patients, showing their role in thrombotic complications.

Frontiers in Immunology · Mar 3, 2022Peer-reviewedImmunology

Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine

R. R. Goel, M. M. Painter, K. A. Lundgreen, S. A. Apostolidis, A. E. Baxter, J. R. Giles, D. Mathew, A. Pattekar, A. Reynaldi, D. S. Khoury, S. Gouma, P. Hicks, S. Dysinger, A. Hicks, H. Sharma, , E. J. Wherry

This study examines antibody and memory B cell responses after a third dose of SARS-CoV-2 mRNA vaccine, showing improved antibody quality and stable memory B cells capable of recognizing multiple variants.

bioRxiv · Feb 20, 2022Immunology

mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern

R. R. Goel, M. M. Painter, S. A. Apostolidis, D. Mathew, W. Meng, A. M. Rosenfeld, K. A. Lundgreen, A. Reynaldi, D. S. Khoury, A. Pattekar, S. Gouma, L. Kuri-Cervantes, P. Hicks, S. Dysinger, A. Hicks, , Set

This study shows that mRNA vaccination generates durable immune memory against SARS-CoV-2 and variants of concern, with continued evolution of B and T cell responses for at least 6 months.

bioRxiv · Aug 23, 2021 · PreprintImmunology

Rapid induction of antigen-specific CD4+ T cells guides coordinated humoral and cellular immune responses to SARS-CoV-2 mRNA vaccination

M. M. Painter, D. Mathew, R. R. Goel, S. A. Apostolidis, A. Pattekar, O. Kuthuru, A. E. Baxter, R. S. Herati, D. A. Oldridge, S. Gouma, P. Hicks, S. Dysinger, K. A. Lundgreen, L. Kuri-Cervantes, S. Adamski, , E. J. Wherry

This study shows that mRNA vaccination rapidly induces antigen-specific CD4+ T cells, which coordinate humoral and cellular immune responses, with booster doses enhancing T cell responses in naive individuals.

bioRxiv · Apr 21, 2021 · PreprintImmunology