Author

D. S. Khoury

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:scRNA-seq· 3 Research Focus:cell signaling & trafficking· 2

Frequent Co-Authors

A. Haque· 3 shared C. G. Williams· 3 shared H. J. Lee· 3 shared J. A. Engel· 3 shared M. P. Davenport· 3 shared M. S. F. Soon· 3 shared A. E. Baxter· 2 shared A. Hicks· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

A. Haque

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

The delayed bloodstream clearance of Plasmodium falciparum parasites after M5717 treatment is attributable to the inability to modify their red blood cell hosts.

M. P. Schneider, O. Looker, M. Rebelo, D. S. Khoury, M. W. Dixon, C. Oeuvray, B. S. Crabb, J. McCarthy, P. R. Gilson

This study shows M5717 delays Plasmodium falciparum parasite clearance by preventing host RBC modification, leading to reduced cytoadherence and splenic clearance.

bioRxiv · Apr 24, 2023 · PreprintMicrobiology

Spatial transcriptomics maps molecular and cellular requirements for CD4+ T cell-dependent immunity to malaria.

C. G. Williams, M. d. L. Moreira, T. Asatsuma, O. P. Skinner, H. J. Lee, S. Li, I. Barrera, E. Murray, M. S. F. Soon, J. A. Engel, D. S. Khoury, S. Asad, T. M. Steiner, R. Joseph, Y. Alexandre, , A. Haque

This paper uses spatial transcriptomics to map CD4+ T cell and B cell interactions in the spleen during malaria infection, revealing their localization and molecular requirements for immunity.

bioRxiv · Feb 23, 2023 · PreprintImmunology

Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine

R. R. Goel, M. M. Painter, K. A. Lundgreen, S. A. Apostolidis, A. E. Baxter, J. R. Giles, D. Mathew, A. Pattekar, A. Reynaldi, D. S. Khoury, S. Gouma, P. Hicks, S. Dysinger, A. Hicks, H. Sharma, , E. J. Wherry

This study examines antibody and memory B cell responses after a third dose of SARS-CoV-2 mRNA vaccine, showing improved antibody quality and stable memory B cells capable of recognizing multiple variants.

bioRxiv · Feb 20, 2022Immunology

mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern

R. R. Goel, M. M. Painter, S. A. Apostolidis, D. Mathew, W. Meng, A. M. Rosenfeld, K. A. Lundgreen, A. Reynaldi, D. S. Khoury, A. Pattekar, S. Gouma, L. Kuri-Cervantes, P. Hicks, S. Dysinger, A. Hicks, , Set

This study shows that mRNA vaccination generates durable immune memory against SARS-CoV-2 and variants of concern, with continued evolution of B and T cell responses for at least 6 months.

bioRxiv · Aug 23, 2021 · PreprintImmunology

Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites

L. I. M. Lansink, J. A. Engel, H. J. Lee, M. S. F. Soon, C. G. Williams, A. SheelaNair, C. P. S. Pernold, P. Laohamonthonkul, J. Akter, T. Stoll, M. M. Hill, A. M. Talman, A. J. C. Russell, M. Lawniczak, M. P. Davenport, , A. Haque

The paper shows that systemic host inflammation slows malaria parasite maturation and alters their transcriptomic profile in vivo.

bioRxiv · Aug 18, 2021Microbiology

Transcriptome Dynamics Reveals Progressive Transition from Effector to Memory in CD4+ T cells.

M. S. F. Soon, H. J. Lee, J. A. Engel, J. Straube, B. S. Thomas, L. S. Clarke, P. Laohamonthonkul, C. P. S. Pernold, R. N. Haldar, C. G. Williams, L. I. M. Lansink, R. Koufariotis, V. Lakis, S. Wood, X. Chen, , A. Haque

This study uses single-cell RNA-seq and ATAC-seq to show a progressive transition from effector to memory CD4+ T cells during Plasmodium infection, with linear pathways and memory-associated gene expression.

bioRxiv · Jun 19, 2019 · PreprintImmunology