Author

R. S. Flannagan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

D. E. Heinrichs· 3 shared B. Kumar· 1 shared H. C. Craig· 1 shared I. Z. Batko· 1 shared J. Choi· 1 shared J. J. Power· 1 shared J. K. McCormick· 1 shared J. R. Brozyna· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

D. E. Heinrichs

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In vivo growth of Staphylococcus lugdunensis is facilitated by the concerted function of heme and non-heme iron acquisition mechanisms

R. S. Flannagan, J. R. Brozyna, B. Kumar, L. A. Adolf, J. J. Power, S. Heilbronner, D. E. Heinrichs

This study identifies the iron acquisition mechanisms used by Staphylococcus lugdunensis during infection, showing that both heme and non-heme iron systems are required for proliferation in mice.

bioRxiv · Jan 12, 2022Microbiology

Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma (IFNγ) production that subverts macrophage function

S. W. Tuffs, M. I. Goncheva, S. X. Xu, H. C. Craig, K. J. Kasper, J. Choi, R. S. Flannagan, S. M. Kerfoot, D. E. Heinrichs, J. K. McCormick

This study shows that staphylococcal superantigens increase S. aureus bloodstream infection severity by inducing high IFNγ production, which impairs macrophage function and allows bacterial survival.

bioRxiv · Aug 17, 2021Microbiology

Heme-dependent siderophore utilization promotes iron-restricted growth of the Staphylococcus aureus hemB small colony variant

I. Z. Batko, R. S. Flannagan, V. Guariglia-Oropeza, J. R. Sheldon, D. E. Heinrichs

This study shows that heme-dependent siderophore utilization is critical for iron acquisition by hemB S. aureus SCVs, enabling growth under iron restriction and in vivo.

bioRxiv · Jun 29, 2021Microbiology