Author

S. W. Tuffs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

H. C. Craig· 2 shared J. K. McCormick· 2 shared B. A. Shannon· 1 shared D. E. Heinrichs· 1 shared J. Choi· 1 shared J. R. Hurst· 1 shared K. J. Kasper· 1 shared M. I. Goncheva· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

H. C. Craig

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Author profile →

2 papers

Recent·Most cited

The Streptococcus pyogenes hyaluronic acid capsule promotes experimental nasal and skin infection by preventing neutrophil-mediated clearance

J. R. Hurst, B. A. Shannon, H. C. Craig, S. W. Tuffs, J. K. McCormick

This study shows that the hyaluronic acid capsule of Streptococcus pyogenes protects against neutrophil-mediated killing during nasal and skin infections, increasing bacterial burden.

bioRxiv · Apr 7, 2022Microbiology

Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma (IFNγ) production that subverts macrophage function

S. W. Tuffs, M. I. Goncheva, S. X. Xu, H. C. Craig, K. J. Kasper, J. Choi, R. S. Flannagan, S. M. Kerfoot, D. E. Heinrichs, J. K. McCormick

This study shows that staphylococcal superantigens increase S. aureus bloodstream infection severity by inducing high IFNγ production, which impairs macrophage function and allows bacterial survival.

bioRxiv · Aug 17, 2021Microbiology