Author

S. X. Xu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

D. E. Heinrichs· 1 shared H. C. Craig· 1 shared J. Choi· 1 shared J. K. McCormick· 1 shared K. J. Kasper· 1 shared M. I. Goncheva· 1 shared R. S. Flannagan· 1 shared S. M. Kerfoot· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

D. E. Heinrichs

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1 paper

Recent·Most cited

Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma (IFNγ) production that subverts macrophage function

S. W. Tuffs, M. I. Goncheva, S. X. Xu, H. C. Craig, K. J. Kasper, J. Choi, R. S. Flannagan, S. M. Kerfoot, D. E. Heinrichs, J. K. McCormick

This study shows that staphylococcal superantigens increase S. aureus bloodstream infection severity by inducing high IFNγ production, which impairs macrophage function and allows bacterial survival.

bioRxiv · Aug 17, 2021Microbiology