R. S. Smith

Robust planar morphogenesis in leaf-like organs requires callose-dependent coordination of division and growth

This study shows that callose-dependent coordination between cell division and growth is essential for planar morphogenesis in moss phyllids.

A deep learning-based toolkit for 3D nuclei segmentation and quantitative analysis in cellular and tissue context

The paper introduces computational tools for 3D nuclei segmentation and analysis, showing variations in nuclear-to-cell volume ratios across tissues.

SHOOTMERISTEMLESS autoactivation: A prerequisite for fruit metamorphosis

The paper shows that CrSTM autoactivation through a cis regulatory element is essential for Capsella fruit shape transition during metamorphosis.

Growth history leaves a geometric trace in puzzle cells

The paper shows that puzzle-shaped cells record tissue growth history through geometric changes, validated in maize and Arabidopsis with mechanical simulations and imaging.

Growth and tension in explosive fruit

The paper investigates how tension in exploding seed pods of Cardamine hirsuta is generated through active cell growth and microtubule-controlled cellulose microfibril orientation.

Genetic control of cell layer interactions in plants via tissue mechanics

The paper shows that brassinosteroid genes control tissue growth coordination in plants by modulating mechanical constraints between cell layers.

Cell growth rates coordinate across the width of the leaf to remain flat

The paper analyzes cell growth dynamics in Arabidopsis leaves to show that coordinated growth across the leaf blade is necessary for maintaining flatness, and that the jaw-D mutant disrupts this coordination.

The annotation and analysis of complex 3D plant organs using 3DCoordX

The paper develops 3DCoordX, a tool for spatially annotating cells in 3D plant organs, revealing new insights into growth patterns across species.

Establishment of multiple novel patient-derived models of desmoplastic small round cell tumor enabling functional characterization of ERBB pathway signaling and pre-clinical evaluation of a novel targeted therapy approach

This study develops new DSRCT models and shows that targeting the ERBB pathway with EGFR inhibitors reduces tumor growth in preclinical models.

A digital 3D reference atlas reveals cellular growth patterns shaping the Arabidopsis ovule

The paper creates a 3D digital atlas of Arabidopsis ovule development, revealing cellular growth patterns and new functions in morphogenesis.

Timing of organ initiation is crucial for robust organ size

The paper shows that DRMY1 regulates sepal size in Arabidopsis by controlling organ initiation timing and growth.