Author

R. Sealfon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

J. Zhou· 2 shared O. G. Troyanskaya· 2 shared A. Boppana· 1 shared A. D. Kim· 1 shared A. D. Smith· 1 shared A. Gladfelter· 1 shared A. P. McMahon· 1 shared A. Ransick· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersScientific Communication & Education

J. Zhou

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Multimodal and Integrated Approach to Interrogate Human Kidney Biopsies with Rigor and Reproducibility: The Kidney Precision Medicine Project

T. M. El-Achkar, M. T. Eadon, R. Menon, B. B. Lake, T. K. Sigdel, T. Alexandrov, S. Parikh, G. Zhang, D. Dobi, K. W. Dunn, E. A. Otto, C. R. Anderton, J. M. Carson, J. Luo, C. Park, , For the Kidney Precision Medicine Project

The paper describes a pipeline for generating 3D molecular atlases of human kidney biopsies using multi-OMICS and imaging technologies, emphasizing quality control and reproducibility across institutions.

bioRxiv · Aug 23, 2020 · PreprintScientific Communication & Education

Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate

C. Iserman, C. A. Roden, M. Boerneke, R. Sealfon, G. McLaughlin, I. Jungreis, C. Y. Park, A. Boppana, E. Fritch, Y. Hou, C. Theesfeld, O. Troyanskaya, R. S. G. Baric, T. P. Sheahan, K. Weeks, A. Gladfelter

This study shows SARS-CoV-2 N-protein forms liquid-liquid phase separation with specific viral RNA sequences, which is temperature-sensitive and can be modulated by small molecules, offering potential for antiviral drug development.

bioRxiv · Jun 11, 2020 · PreprintBiochemistry

Spatial Transcriptional Mapping of the Human Nephrogenic Program

N. O. Lindstrom, R. Sealfon, X. Chen, R. Parvez, A. Ransick, G. De Sena Brandine, J. Guo, B. Hill, T. Tran, A. D. Kim, J. Zhou, A. Tadych, A. Watters, A. Wong, E. Lovero, , A. P. McMahon

The paper spatially maps the human nephrogenic program using single-cell RNA sequencing and generates functional gene-networks to identify developmental disease genes and predict new targets.

bioRxiv · Apr 27, 2020Cell Biology