Author

J. Grimes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

E. Fodor· 2 shared A. Baazaoui· 1 shared A. K. Shukla· 1 shared A. P. Walker· 1 shared B. Medel-Lacruz· 1 shared D. Calebiro· 1 shared D. M. Owen· 1 shared H. Fan· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

E. Fodor

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural and functional characterisation of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA Polymerase II

J. Keown, A. Baazaoui, M. Sebesta, R. Stefl, L. Carrique, E. Fodor, J. Grimes

This study characterizes the structural and functional interaction between influenza A virus RNA polymerase and host RNA Polymerase II CTD, identifying key residues and their roles in transcription and replication.

bioRxiv · Nov 29, 2023 · PreprintMicrobiology

Single-molecule analysis of receptor-beta-arrestin interactions in living cells

J. Grimes, Z. Koszegi, Y. Lanoiselee, T. Miljus, S. L. O'Brien, T. M. Stepniewski, B. Medel-Lacruz, M. Baidya, M. Makarova, D. M. Owen, A. K. Shukla, J. Selent, S. J. Hill, D. Calebiro

This study uses single-molecule microscopy and simulations to show that beta-arrestin inserts into the lipid bilayer and interacts with receptors through lateral diffusion, challenging existing models of its function.

bioRxiv · Nov 15, 2022 · PreprintCell Biology

Identification of guanylyltransferase activity in the SARS-CoV-2 RNA polymerase

A. P. Walker, H. Fan, J. R. Keown, J. Grimes, E. Fodor

This paper identifies the guanylyltransferase activity in SARS-CoV-2 RNA polymerase and shows remdesivir triphosphate inhibits both GTase and polymerase functions.

bioRxiv · Mar 17, 2021 · PreprintMicrobiology