Author

R. T. Beacham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:electrophysiology· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. R. Rodan· 2 shared A. R. Subramanya· 2 shared C. R. Boyd-Shiwarski· 2 shared D. J. Shiwarski· 2 shared S. E. Griffiths· 2 shared A. Bandaru· 1 shared A. L. Marciszyn· 1 shared C. C. Weckerly· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

A. R. Rodan

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

WNK kinases sense molecular crowding and rescue cell volume via phase separation

C. R. Boyd-Shiwarski, D. J. Shiwarski, S. E. Griffiths, R. T. Beacham, L. Norrell, D. E. Morrison, J. Wang, J. R. Mann, W. Tennant, E. N. Anderson, J. Franks, M. Calderon, K. A. Connolly, C. J. Weaver, C. C. Weckerly, , A. R. Subramanya

This study shows WNK1 senses molecular crowding by phase separation to activate volume recovery in hypertonic conditions through phosphorylation-dependent signaling.

bioRxiv · Jan 10, 2022Cell Biology

KS-WNK1 amplifies kidney tubule responsiveness to potassium via WNK body condensates

C. R. Boyd-Shiwarski, R. T. Beacham, J. A. Lashway, K. E. Querry, S. E. Griffiths, D. J. Shiwarski, S. A. Knoell, N. H. Nguyen, L. J. Nkashama, M. N. Valladares, A. Bandaru, A. L. Marciszyn, A. R. Rodan, C.-L. Huang, S. D. Stocker, , A. R. Subramanya

This study shows KS-WNK1 amplifies NCC activity in response to potassium changes via WNK bodies, leading to sex-specific renal salt-wasting and blood pressure sensitivity.

bioRxiv · Mar 12, 2021 · PreprintPhysiology