Author

C.-L. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Bioengineering· 1 Biophysics· 1 Cell Biology· 1 Ecology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:cell type annotation· 5 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

A. Bandaru· 1 shared A. Banks· 1 shared A. Chen· 1 shared A. Commodaro· 1 shared A. Ekayanti· 1 shared A. J. Trzeciak· 1 shared A. L. Marciszyn· 1 shared A. Lipshutz· 1 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPhysiology

A. Bandaru

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Proteomic profile analysis of plasma and aqueous humor from glaucoma and non-glaucomatous patients

C. L. Pessuti, C.-L. Huang, A. Banks, N. Vo, L. Jennings, J. Loureiro, K. Ribeiro, D. F. Costa, H. Nascimento, C. Muccioli, I. M. Tavares, A. Commodaro, R. Belfort, C. Wilson, A. Chen, , V. Raghunathan

This study compares proteomic profiles of aqueous humor and plasma between glaucoma and non-glaucomatous patients, identifying differentially abundant proteins linked to vascular integrity, inflammation, and neurodegeneration.

bioRxiv · Apr 11, 2024 · PreprintCell Biology

Conformational landscape of soluble α-klotho revealed by cryogenic electron microscopy

N. J. Schnicker, Z. Xu, M. Amir, L. Gakhar, C.-L. Huang

This study reveals the conformational landscape of soluble α-klotho using cryo-EM, showing flexibility and multiple forms that support its FGFR-independent functions.

bioRxiv · Mar 2, 2024 · PreprintBiophysics

Transport activity regulates mitochondrial bioenergetics and biogenesis in renal tubules

C.-J. Cheng, J. M. Nizar, D.-F. Dai, C.-L. Huang

This paper develops an extracellular flux analysis to study mitochondrial respiration and energy metabolism in isolated renal tubules, showing transport activity regulates mitochondrial bioenergetics and biogenesis.

bioRxiv · Feb 4, 2024Physiology

Effects of local and landscape factors on paddy field arthropod diversity: from species to communities

J.-A. Ou, C.-L. Huang, C.-W. Tsai, C.-K. Ho

This study examines how local and landscape factors influence paddy field arthropod diversity, finding that environmental effects are highly species-specific and that species richness is more influenced by landscape factors than local ones.

bioRxiv · Jan 17, 2024 · PreprintEcology

WNK1 enforces macrophage lineage fidelity

A. J. Trzeciak, W. S. Rojas, Z.-L. Liu, A. S. Krebs, Z. Wang, P. H. V. Saavedra, I. C. Miranda, A. Lipshutz, J. Xie, C.-L. Huang, M. Overholtzer, M. S. Glickman, C. N. Parkhurst, T. Vierbuchen, C. D. Lucas, J. S. A. Perry

This paper identifies WNK1 as essential for macrophage lineage fidelity, showing its role in preventing myeloid progenitors from differentiating into neutrophils.

bioRxiv · Apr 26, 2023 · PreprintImmunology

Refined novel techniques for long term cryo-storage using vitrification and laser warming

C. Lin, W.-C. Hsieh, K. Loeslakwiboon, C.-L. Huang, T.-C. Chen, S. Tsai

The paper develops a customized cryo-jig for improved laser striking accuracy and rewarming success in long-term cryo-storage using vitrification and laser warming.

bioRxiv · Jan 4, 2023Bioengineering

KS-WNK1 amplifies kidney tubule responsiveness to potassium via WNK body condensates

C. R. Boyd-Shiwarski, R. T. Beacham, J. A. Lashway, K. E. Querry, S. E. Griffiths, D. J. Shiwarski, S. A. Knoell, N. H. Nguyen, L. J. Nkashama, M. N. Valladares, A. Bandaru, A. L. Marciszyn, A. R. Rodan, C.-L. Huang, S. D. Stocker, , A. R. Subramanya

This study shows KS-WNK1 amplifies NCC activity in response to potassium changes via WNK bodies, leading to sex-specific renal salt-wasting and blood pressure sensitivity.

bioRxiv · Mar 12, 2021 · PreprintPhysiology

DNA barcodes and reliable molecular identifications in a diverse group of invasive pests: lessons from Bactrocera fruit flies on variation across the COI gene, introgression, and standardization

C. Doorenweerd, M. San Jose, L. Leblanc, N. Barr, S. Geib, A. Y. C. Chung, J. Dupuis, A. Ekayanti, E. Fiegalan, K. S. Hemachandra, M. A. Hossain, C.-L. Huang, Y.-F. Hsu, K. Y. Morris, A. Maryani Mustapeng, , D. Rubinoff

The paper evaluates the effectiveness of COI gene sequences for species identification in Dacini fruit flies, finding high congruence with morphology but also introgression issues in some pest species.

bioRxiv · Nov 23, 2020 · PreprintEvolutionary Biology

Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin

P. Zhou, X.-L. Yang, X.-G. Wang, B. Hu, L. Zhang, W. Zhang, H.-R. Si, Y. Zhu, B. Li, C.-L. Huang, H.-D. Chen, J. Chen, Y. Luo, H. Guo, R.-D. Jiang, , Z.-L. Shi

This paper identifies and characterizes a novel coronavirus (nCoV-2019) causing a human pneumonia outbreak, showing its close genetic relationship to bat coronaviruses and its use of the ACE2 receptor for cell entry.

Nature · Feb 3, 2020Peer-reviewedMicrobiology