Author

D. J. Shiwarski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 5 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 5 Assay:imaging· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Organism:mouse· 2 Assay:organoid / primary culture· 2

Frequent Co-Authors

A. W. Feinberg· 5 shared J. W. Tashman· 4 shared A. R. Rodan· 2 shared A. R. Subramanya· 2 shared C. R. Boyd-Shiwarski· 2 shared J. M. Bliley· 2 shared R. N. Palchesko· 2 shared R. T. Beacham· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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5 shared papersBioengineering

A. W. Feinberg

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

3D Bioprinting of Collagen-based Microfluidics for Engineering Fully-biologic Tissue Systems

D. J. Shiwarski, A. R. Hudson, J. W. Tashman, E. Bakirci, S. P. Moss, B. D. Coffin, A. W. Feinberg

The paper develops a 3D bioprinting method to create microfluidic collagen-based scaffolds that support vascularized, pancreatic-like tissue systems for disease modeling and drug discovery.

bioRxiv · Jan 26, 2024 · PreprintBioengineering

WNK kinases sense molecular crowding and rescue cell volume via phase separation

C. R. Boyd-Shiwarski, D. J. Shiwarski, S. E. Griffiths, R. T. Beacham, L. Norrell, D. E. Morrison, J. Wang, J. R. Mann, W. Tennant, E. N. Anderson, J. Franks, M. Calderon, K. A. Connolly, C. J. Weaver, C. C. Weckerly, , A. R. Subramanya

This study shows WNK1 senses molecular crowding by phase separation to activate volume recovery in hypertonic conditions through phosphorylation-dependent signaling.

bioRxiv · Jan 10, 2022Cell Biology

In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography

J. W. Tashman, D. J. Shiwarski, A. Ruesch, F. Lanni, J. Kainerstorfer, A. W. Feinberg

This paper develops an OCT-integrated FRESH bioprinting platform for high-fidelity 3D volumetric imaging and real-time defect detection in bioprinted constructs.

bioRxiv · Jun 30, 2021Bioengineering

KS-WNK1 amplifies kidney tubule responsiveness to potassium via WNK body condensates

C. R. Boyd-Shiwarski, R. T. Beacham, J. A. Lashway, K. E. Querry, S. E. Griffiths, D. J. Shiwarski, S. A. Knoell, N. H. Nguyen, L. J. Nkashama, M. N. Valladares, A. Bandaru, A. L. Marciszyn, A. R. Rodan, C.-L. Huang, S. D. Stocker, , A. R. Subramanya

This study shows KS-WNK1 amplifies NCC activity in response to potassium changes via WNK bodies, leading to sex-specific renal salt-wasting and blood pressure sensitivity.

bioRxiv · Mar 12, 2021 · PreprintPhysiology

Injury-Free In Vivo Delivery and Engraftment into the Cornea Endothelium Using Extracellular Matrix Shrink-Wrapped Cells

R. N. Palchesko, Y. Du, M. Geary, S. Carrasquilla, D. J. Shiwarski, I. Khandaker, J. L. Feunderburgh, A. W. Feinberg

The paper develops a method to shrink-wrap corneal endothelial cells in extracellular matrix for improved engraftment, increasing cell density in the cornea.

bioRxiv · Mar 1, 2021 · PreprintBioengineering

Dynamic Loading of Human Engineered Heart Tissue Enhances Contractile Function and Drives Desmosome-linked Disease Phenotype

J. M. Bliley, M. Vermeer, R. M. Duffy, I. Batalov, D. Kramer, J. W. Tashman, D. J. Shiwarski, A. Lee, A. S. Teplenin, L. Volkers, B. Coffin, M. F. Hoes, A. Kalmykov, R. N. Palchesko, Y. Sun, , A. W. Feinberg

The paper develops a dynamic EHT model to enhance contractile function and study desmosome-linked disease phenotypes in engineered heart tissues.

bioRxiv · May 25, 2020Bioengineering

Fibronectin-Based Nanomechanical Biosensors to Map 3D Strains in Live Cells and Tissues

D. J. Shiwarski, J. W. Tashman, A. Tsamis, J. M. Bliley, M. A. Blundon, E. Aranda-Michel, Q. Jallerat, J. M. Szymanski, B. M. McCartney, A. W. Feinberg

This paper introduces a fibronectin-based nanomechanical biosensor to measure strain in live cells and tissues with high spatial resolution and minimal perturbation.

bioRxiv · Feb 11, 2020Bioengineering