Pharmacology & ToxicologybioRxiv
The Multidrug Resistance Transporter P-glycoprotein Confers Resistance to Ferroptosis Inducers
W. J. E. Frye, L. M. Huff, J. M. G. Dalmasy…·M. M. Gottesman
This study shows that P-glycoprotein (P-gp) and ABCG2 confer resistance to ferroptosis inducers, and some inducers inhibit these transporters, suggesting potential drug-drug interactions.
DOI 10.20517/cdr.2023.29