Author

R. W. Stam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Closa· 2 shared E. Eyras· 2 shared A. Bataller· 1 shared A. C. Fuentes-Fayos· 1 shared A. Thomas-Tikhonenko· 1 shared C. Bueno· 1 shared C. Mullighan· 1 shared F. Abollo-Jimenez· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

A. Closa

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A comprehensive single-cell expression atlas of human AML leukemia-initiating cells unravels the contribution of HIF pathway and its therapeutic potential

T. Velasco-Hernandez, J. L. Trincado, M. Vinyoles, A. Closa, F. Gutierrez-Aguera, O. Molina, V. C. Rodriguez-Cortez, P. Petazzi, S. Beneyto-Calabuig, L. Velten, P. Romecin, R. Casquero, F. Abollo-Jimenez, R. Diaz de la Guardia, P. Lorden, , P. Menendez

The paper creates a single-cell atlas of AML leukemia-initiating cells and shows that targeting the HIF pathway enhances chemotherapy effectiveness against these cells.

bioRxiv · Mar 2, 2022 · PreprintCancer Biology

A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1

A. Closa, M. Reixachs-Sole, A. C. Fuentes-Fayos, K. E. Hayer, J. L. Melero, F. R. Adriaanse, R. S. Bos, M. Torres-Diz, S. Hunger, K. G. Roberts, C. Mullighan, R. W. Stam, A. Thomas-Tikhonenko, J. P. Castano, R. M. Luque, E. Eyras

The paper identifies a convergent malignant phenotype in infant B-ALL linked to SRRM1 upregulation and splicing alterations, independent of gene fusions.

bioRxiv · Dec 13, 2021 · PreprintCancer Biology