Author

R. W. Wiseman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:non-human primate· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-exome sequencing· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

D. H. O'Connor· 2 shared A. A. Lackner· 1 shared A. J. Ericsen· 1 shared A. O. Jordan· 1 shared B. F. Keele· 1 shared B. Haggarty· 1 shared B. Pahar· 1 shared C. C. LaBranche· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

D. H. O'Connor

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Author profile →

3 papers

Recent·Most cited

A tyrosine-based trafficking signal in the simian immunodeficiency virus envelope cytoplasmic domain is strongly selected for in pathogenic SIV infection

S. Lawrence, S. E. Elser, W. Torben, R. V. Blair, B. Pahar, P. P. Aye, F. Schiro, D. Szeltner, L. A. Doyle-Meyers, B. Haggarty, A. O. Jordan, J. Romano, X. Alvarez, D. H. O'Connor, R. W. Wiseman, , J. A. Hoxie

This study shows that a tyrosine-based trafficking signal in SIV Env is strongly selected for during pathogenic infection, as mutations reconstitute endocytosis and polarized sorting signals.

bioRxiv · Mar 31, 2021 · PreprintCell Biology

Identification of a lymphocyte minor histocompatibility antigen in Mauritian cynomolgus macaques

J. T. Weinfurter, M. E. Graham, A. J. Ericsen, L. M. Matschke, S. Llewellyn-Lacey, D. A. Price, R. W. Wiseman, M. R. Reynolds

The paper identifies a minor histocompatibility antigen in Mauritian cynomolgus macaques using alloimmunization, exome sequencing, and bioinformatics, showing its potential as a target for HIV immunotherapies.

bioRxiv · Jun 10, 2020 · PreprintImmunology

MHC genotyping from rhesus macaque exome sequences

J. R. Caskey, R. W. Wiseman, J. A. Karl, D. A. Baker, T. Lee, M. Raveendran, R. A. Harris, J. Hu, D. M. Muzny, J. Rogers, D. H. O'Connor

This study introduces a method to genotype MHC class I and II from rhesus macaque exome sequences with high accuracy, outperforming conventional methods.

bioRxiv · May 2, 2019Immunology