Author

Robert Mitchell

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genetic & Genomic Medicine· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:fine-mapping· 2 Assay:GWAS summary statistics· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Alexander J. ClarkeiD· 2 shared Carole OberiD· 2 shared Emma E. ThompsoniD· 2 shared Isabella M. SalamoneiD· 2 shared Marcelo A. NóbregaiD· 2 shared Nathan SchoettleriD· 2 shared Noboru J. SakabeiD· 2 shared Xiaoyuan ZhongiD· 2 shared

Activity by Year

2025-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Alexander J. ClarkeORCID

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Author profile →

4 papers

Recent·Most cited

Glycogen synthase kinase-3 is essential for Treg development and function

Matheswaran Kandasamy, Hana F. Andrew, Iwan G. A. Raza, Robert Mitchell, Mariana Borsa, Salvatore Valvo, Mohammad A. Ali, Barbara Kronsteiner, Moustafa Attar, Alexander J. Clarke

This study shows that GSK3 is essential for Treg development and function, as its loss leads to metabolic changes, pro-inflammatory gene expression, and enhanced anti-tumoral immunity.

Cell Reports · Sep 1, 2025Peer-reviewedImmunology

TASL is required for age-related B cell formation and autoimmunity

Julia C. Johnstone, Robert Mitchell, Alexander J. Clarke

This study shows TASL is essential for age-related B cell formation and autoimmunity in a lupus mouse model, but not for B cell development.

bioRxiv · Aug 1, 2025 · PreprintImmunology

Shared loci but distinct variants underlie genetic architecture of allergic diseases

Isabella M. Salamone, Xiaoyuan Zhong, Noboru J. Sakabe, Robert Mitchell, William Wentworth-Sheilds, Li Zhang, Emma E. Thompson, Donna C. Decker, Clayton H. Rische, Xuanyao Liu, Nathan Schoettler, Carole Ober, Xin He, Marcelo A. Nóbrega

The paper identifies disease-specific risk variants and shared effector genes in allergic diseases using functional fine-mapping and expression quantitative trait loci.

medRxiv · Jun 6, 2025 · PreprintGenetic & Genomic Medicine

Integration of functional genomics and statistical fine-mapping systematically characterizes adult-onset and childhood-onset asthma genetic associations.

Xiaoyuan Zhong, Robert Mitchell, Christine Billstrand, Emma E. Thompson, Noboru J. Sakabe, Ivy Aneas, Isabella M. Salamone, Jing Gu, Anne I. Sperling, Nathan Schoettler, Marcelo A. Nóbrega, Xin He, Carole Ober

This study integrates functional genomics and statistical fine-mapping to identify causal variants, regulatory elements, and effector genes for adult-onset and childhood-onset asthma.

Genome Medicine · Apr 9, 2025Peer-reviewedGenetic & Genomic Medicine