Mariana Borsa

The paper shows that transient immune architecture changes during infection protect low-affinity CD8 T-cell priming from Treg inhibition, ensuring broad T-cell responses.

This study shows that autophagy regulates asymmetric inheritance of old mitochondria in CD8+ T cells, which influences their metabolic state and memory potential.

This study shows that autophagy in adipocytes limits obesity-related fibrosis by controlling purine nucleoside metabolism and macrophage polarization.

This study shows that GSK3 is essential for Treg development and function, as its loss leads to metabolic changes, pro-inflammatory gene expression, and enhanced anti-tumoral immunity.