Yeast-based production platform for potent and stable heavy chain-only antibodies
Chiara Lonigro, Hannah Eeckhaut, Royan Alipour Symakani, Kenny Roose, Bert Schepens, Koen Sedeyn, Anne-Sophie de Smet, Jackeline Cecilia Zavala Marchan, Pieter Vanhaverbeke, Sandrine Vanmarcke, Katrien Claes, Sieglinde De Cae, Hans Demol, Simon Devos, Daria Fijałkowska, , Nico Callewaert
This paper presents a yeast-based platform for producing stable and potent heavy chain-only antibodies, demonstrating its effectiveness with an anti-SARS-CoV-2 example.
bioRxiv · Mar 4, 2024 · PreprintMicrobiology