Author

Ron Siaden-Ortega

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Julien MarcouxiD· 2 shared Andrea Gomes· 1 shared Anthony David· 1 shared Ariane AbrieuiD· 1 shared Arnaud MétaisiD· 1 shared Audrey Guesdon· 1 shared Aymeric NeyretiD· 1 shared Bastien SuireiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Julien MarcouxORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In vitro reconstitution defines the mechanistic basis of HSET motor activity regulation by IntraFlagellar Transport proteins

Audrey Guesdon, Valérie Simon, Ron Siaden-Ortega, Juliette van Dijk, Julien Marcoux, Bénédicte Delaval, Benjamin Vitre

This study uses an in vitro reconstitution system to show that IFT proteins enhance HSET kinesin processivity, promoting microtubule sliding and centrosome clustering.

Communications Biology · Apr 10, 2026Peer-reviewedCell Biology

A TAK1-Driven NLRP1 Inflammasome Pathway Revealed by Phosphatase-Targeting Environmental Toxins

M. Paradis, Léana Gorse, Leandro Silva da Costa, Rae Chua, Geraldine Aberola, Arnaud Métais, Ludovic Batistic, Thomas Benoist, Anthony David, Emeline Pagès, Andrea Gomes, Caio César Barbosa Bomfim, Léa Ravon‐Katossky, Bastien Suire, Léa Fromont, , Étienne Meunier

The paper identifies PP1 and PP2A phosphatases as regulators of NLRP1 inflammasome activation, showing that environmental toxins and viral infections trigger this pathway via TAK1 and p38 kinases.

bioRxiv · Jan 25, 2026 · PreprintImmunology

The kinesin Kip2 promotes microtubule growth using a bipartite polymerase module to deliver tubulin to microtubule plus-ends

Simos Nadalis, Aymeric Neyret, Ioanna Xanthou, Ron Siaden-Ortega, Julien Marcoux, Ariane Abrieu, Hauke Drechsler, Dimitris Liakopoulos, Didier Portran

This study identifies the mechanism by which Kip2 promotes microtubule growth through a bipartite polymerase module that delivers tubulin to microtubule plus-ends.

Cell Reports · Sep 27, 2025Peer-reviewedCell Biology