Author

Rose Lempers

The Netherlands Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anna Their· 1 shared Bram ThijsseniD· 1 shared Chrysiida BaltiraiD· 1 shared Daria M. FedorushkovaiD· 1 shared Ferhat AlkaniD· 1 shared Fleur JochemsiD· 1 shared Hans Janssen· 1 shared Isabel Mayayo‐Peralta· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Anna Their

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1 paper

Recent·Most cited

Mitochondrial damage triggers therapy-induced senescence

Chrysiida Baltira, Ferhat Alkan, Isabel Mayayo‐Peralta, Míriam Guillén Navarro, Bram Thijssen, Rose Lempers, Kimberley Pello, Daria M. Fedorushkova, Anna Their, Fleur Jochems, Kicky Rozing, Onno B. Bleijerveld, Hans Janssen, Laura E. Kuil, Jos H. Beijnen, , Mark C. de Gooijer

The paper shows that mitochondrial damage can induce therapy-induced senescence in GBM cells through a ROS-cGAS-STING-SASP cascade, outperforming single or dual pathway inhibitors.

bioRxiv · Dec 20, 2024 · PreprintCell Biology